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    CG30062 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246428, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30062provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050062
    Locus tag
    Dmel_CG30062
    See related
    AllianceGenome:FB:FBgn0050062
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG30062
    Summary
    Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular space. Orthologous to human LYZ (lysozyme). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30062 in Genome Data Viewer
    Location:
    50A9-50A9; 2-68 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13445700..13446309, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9333205..9333814, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene ATPase 8A Neighboring gene transfer RNA:Isoleucine-AAT 1-8 Neighboring gene Ser8 Neighboring gene centrosomin Neighboring gene Golgin 97 Neighboring gene arrow Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genomic response to the yeast transcription factor GAL4 in Drosophila. Liu Y, et al. Fly (Austin), 2008 Mar-Apr. PMID 18820459, Free PMC Article
    2. Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Waterhouse RM, et al. Science, 2007 Jun 22. PMID 17588928, Free PMC Article
    3. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    4. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables lysozyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lysozyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lysozyme activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30062-PB
    NP_725299.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13445700..13446309 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165992.3 → NP_725299.2  uncharacterized protein Dmel_CG30062 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725299.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9D5, Q4V5P7
      Conserved Domains (1) summary
      cl00222
      Location:32 → 150
      lysozyme_like; lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z9D5 A1Z9D5

    Gene LinkOut

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