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    CG31928 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326175, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31928provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051928
    Locus tag
    Dmel_CG31928
    See related
    AllianceGenome:FB:FBgn0051928
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10872; Dmel\CG31928
    Summary
    Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in apoptotic process and proteolysis. Located in egg chorion. Orthologous to human PGA3 (pepsinogen A3); PGA4 (pepsinogen A4); and PGA5 (pepsinogen A5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31928 in Genome Data Viewer
    Location:
    22A2-22A2; 2-3 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1492295..1493859)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1492295..1493859)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80. Ewen-Campen B, et al. Proc Natl Acad Sci U S A, 2023 Jun 13. PMID 37276389, Free PMC Article
    2. Transcriptional changes revealed genes and pathways involved in the deficient testis caused by the inhibition of alkaline ceramidase (Dacer) in Drosophila melanogaster. Zhang MJ, et al. Arch Insect Biochem Physiol, 2021 Mar. PMID 33590535
    3. The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila. Landis GN, et al. Aging (Albany NY), 2015 Jan. PMID 25614682, Free PMC Article
    4. Minor proteins and enzymes of the Drosophila eggshell matrix. Fakhouri M, et al. Dev Biol, 2006 May 1. PMID 16515779, Free PMC Article
    5. Identification of transcriptional responsive genes to acetic acid, ethanol, and 2-phenylethanol exposure in Drosophila melanogaster. Seong KM, et al. Pestic Biochem Physiol, 2020 May. PMID 32359537

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in egg chorion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31928-PA
    CG31928-PB
    lysosomal aspartic protease
    NP_001259869.1
    NP_722705.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1492295..1493859
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272940.1 → NP_001259869.1  uncharacterized protein Dmel_CG31928, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259869.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9UN46, Q9VQ11
      Conserved Domains (2) summary
      pfam00026
      Location:91 → 416
      Asp; Eukaryotic aspartyl protease
      cl11403
      Location:84 → 416
      pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases

    2. NM_164418.2 → NP_722705.1  uncharacterized protein Dmel_CG31928, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722705.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9UN46, Q9VQ11
      Related
      FBpp0077594
      Conserved Domains (2) summary
      pfam00026
      Location:91 → 416
      Asp; Eukaryotic aspartyl protease
      cl11403
      Location:84 → 416
      pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQ11 Q9VQ11

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