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    Osi12 Osiris 12 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40766, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Osi12provided by FlyBase
    Official Full Name
    Osiris 12provided by FlyBase
    Primary source
    FLYBASE:FBgn0037419
    Locus tag
    Dmel_CG1154
    See related
    AllianceGenome:FB:FBgn0037419
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1154; Dmel\CG1154; osi12
    Summary
    Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in embryonic dorsal epidermis; embryonic head epidermis; embryonic/larval posterior spiracle; embryonic/larval salivary gland common duct; and larval foregut atrium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Osi12 in Genome Data Viewer
    Location:
    83E2-83E2; 3-47.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6278531..6282495)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2104253..2108217)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Osiris 10b Neighboring gene Osiris 11 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tracheal expression of Osiris gene family in Drosophila. Scholl A, et al. Gene Expr Patterns, 2018 Jun. PMID 29548969
    2. Osiris gene family defines the cuticle nanopatterns of Drosophila. Sun Z, et al. Genetics, 2024 Jun 5. PMID 38652268, Free PMC Article
    3. Conserved roles of Osiris genes in insect development, polymorphism and protection. Smith CR, et al. J Evol Biol, 2018 Apr. PMID 29322640
    4. Evolution of a large, conserved, and syntenic gene family in insects. Shah N, et al. G3 (Bethesda), 2012 Feb. PMID 22384409, Free PMC Article
    5. A family of genes clustered at the Triplo-lethal locus of Drosophila melanogaster has an unusual evolutionary history and significant synteny with Anopheles gambiae. Dorer DR, et al. Genetics, 2003 Oct. PMID 14573474, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    osiris 12
    Names
    CG1154-PA
    Osi12-PA
    osiris

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6278531..6282495
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141374.1 → NP_649631.1  osiris 12 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649631.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNN2
      Related
      FBpp0078251, FBtr0078602
      Conserved Domains (1) summary
      pfam07898
      Location:74 → 159
      DUF1676; Protein of unknown function (DUF1676)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VNN2 Q9VNN2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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