U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG10874 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33394, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG10874provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031395
    Locus tag
    Dmel_CG10874
    See related
    AllianceGenome:FB:FBgn0031395
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10874; FBgn 31395
    Summary
    Predicted to be involved in cilium assembly. Predicted to be located in centrosome. Is expressed in organism. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome and Bardet-Biedl syndrome 1. Orthologous to human CCDC28A (coiled-coil domain containing 28A) and CCDC28B (coiled-coil domain containing 28B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG10874 in Genome Data Viewer
    Location:
    22D1-22D1; 2-5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2189914..2192386, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2189914..2192386, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene transfer RNA:Arginine-TCT 3-1 Neighboring gene long non-coding RNA:CR44066 Neighboring gene long non-coding RNA:CR45290 Neighboring gene antisense RNA:CR44065 Neighboring gene Cytochrome c oxidase subunit 7A-like 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Degeneration of Injured Axons and Dendrites Requires Restraint of a Protective JNK Signaling Pathway by the Transmembrane Protein Raw. Hao Y, et al. J Neurosci, 2019 Oct 23. PMID 31492772, Free PMC Article
    2. Some novel intron positions in conserved Drosophila genes are caused by intron sliding or tandem duplication. Lehmann J, et al. BMC Evol Biol, 2010 May 26. PMID 20500887, Free PMC Article
    3. The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning. Hull R, et al. Int J Mol Sci, 2015 May 6. PMID 25955646, Free PMC Article
    4. Nociceptor-Enriched Genes Required for Normal Thermal Nociception. Honjo K, et al. Cell Rep, 2016 Jul 12. PMID 27346357, Free PMC Article
    5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG10874-PA
    CG10874-PB
    CG10874-PC
    CG10874-PD

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2189914..2192386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164458.5 → NP_722768.2  uncharacterized protein Dmel_CG10874, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722768.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQ84
      Conserved Domains (1) summary
      pfam13270
      Location:121 → 209
      DUF4061; Domain of unknown function (DUF4061)

    2. NM_001258916.3 → NP_001245845.1  uncharacterized protein Dmel_CG10874, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245845.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E4NKL4
      Conserved Domains (1) summary
      pfam13270
      Location:121 → 210
      DUF4061; Domain of unknown function (DUF4061)

    3. NM_134808.4 → NP_608652.1  uncharacterized protein Dmel_CG10874, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608652.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQ83
      Related
      FBpp0077520
      Conserved Domains (1) summary
      pfam13270
      Location:219 → 306
      DUF4061; Domain of unknown function (DUF4061)

    4. NM_001272982.2 → NP_001259911.1  uncharacterized protein Dmel_CG10874, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259911.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PB06
      Conserved Domains (1) summary
      pfam13270
      Location:219 → 307
      DUF4061; Domain of unknown function (DUF4061)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E4NKL4 E4NKL4
    M9PB06 M9PB06
    Q9VQ83 Q9VQ83
    Q9VQ84 Q9VQ84

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools