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    CG10747 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35295, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10747provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032845
    Locus tag
    Dmel_CG10747
    See related
    AllianceGenome:FB:FBgn0032845
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    38B.13; Dmel\CG10747
    Summary
    Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Is expressed in several structures, including adult head; anterior endoderm; anterior endoderm anlage; embryonic/larval midgut; and embryonic/larval midgut primordium. Orthologous to human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2) and PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10747 in Genome Data Viewer
    Location:
    38B5-38B5; 2-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20089636..20091348, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20089636..20091348, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene brain washing Neighboring gene purple Neighboring gene nebbish Neighboring gene fledgling of Klp38B Neighboring gene Pyridine nucleotide-disulfide oxidoreductase domain 1 Neighboring gene TBP-associated factor 13 Neighboring gene nessun dorma

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila. Aikin R, et al. PLoS One, 2012. PMID 22432040, Free PMC Article
    2. Map position and expression of the genes in the 38 region of Drosophila. Butler H, et al. Genetics, 2001 Aug. PMID 11514449, Free PMC Article
    3. Regulation of Drosophila mesoderm migration by phosphoinositides and the PH domain of the Rho GTP exchange factor Pebble. Murray MJ, et al. Dev Biol, 2012 Dec 1. PMID 23000359
    4. Nociceptor-Enriched Genes Required for Normal Thermal Nociception. Honjo K, et al. Cell Rep, 2016 Jul 12. PMID 27346357, Free PMC Article
    5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphoric diester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10747-PA
    CG10747-PB
    NP_001260618.1
    NP_610022.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20089636..20091348 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273689.1 → NP_001260618.1  uncharacterized protein Dmel_CG10747, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXL1, Q9VIP3
      Conserved Domains (1) summary
      cd08616
      Location:10 → 302
      PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

    2. NM_136178.4 → NP_610022.3  uncharacterized protein Dmel_CG10747, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXL1, Q9VIP3
      Related
      FBpp0080873
      Conserved Domains (1) summary
      cd08616
      Location:10 → 302
      PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXL1 Q8SXL1
    Q9VIP3 Q9VIP3

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