U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    nesd nessun dorma [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35298, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    nesdprovided by FlyBase
    Official Full Name
    nessun dormaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032848
    Locus tag
    Dmel_CG10722
    See related
    AllianceGenome:FB:FBgn0032848
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    38B.16; CG10722; Dmel\CG10722
    Summary
    Enables carbohydrate binding activity. Involved in female germline ring canal stabilization and male meiosis cytokinesis. Located in several cellular components, including fusome; male germline ring canal; and midbody. Part of centralspindlin complex. Is expressed in organism and testis. Orthologous to several human genes including SHCBP1 (SHC binding and spindle associated 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See nesd in Genome Data Viewer
    Location:
    38B6-38B6; 2-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20093972..20096253)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20093972..20096253)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene nebbish Neighboring gene uncharacterized protein Neighboring gene Pyridine nucleotide-disulfide oxidoreductase domain 1 Neighboring gene TBP-associated factor 13 Neighboring gene mitochondrial ribosomal protein S18B Neighboring gene Kua

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ectopic assembly of heterochromatin in Drosophila melanogaster triggered by transposable elements. Sentmanat MF, et al. Proc Natl Acad Sci U S A, 2012 Aug 28. PMID 22891327, Free PMC Article
    2. Nessun Dorma, a novel centralspindlin partner, is required for cytokinesis in Drosophila spermatocytes. Montembault E, et al. J Cell Biol, 2010 Dec 27. PMID 21187330, Free PMC Article
    3. Using qualitative probability in reverse-engineering gene regulatory networks. Ibrahim ZM, et al. IEEE/ACM Trans Comput Biol Bioinform, 2011 Mar-Apr. PMID 20876933
    4. What Drosophila spermatocytes tell us about the mechanisms underlying cytokinesis. Giansanti MG, et al. Cytoskeleton (Hoboken), 2012 Nov. PMID 22927345, Free PMC Article
    5. DAPPER: a data-mining resource for protein-protein interactions. Haider S, et al. BioData Min, 2015. PMID 26405458, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in female germline ring canal stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in male meiosis cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in male meiosis cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermatogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of centralspindlin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in female germline ring canal IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fusome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intercellular bridge IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in male germline ring canal IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in midbody IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    nessun dorma
    Names
    CG10722-PA
    CG10722-PB
    nesd-PA
    nesd-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20093972..20096253
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136181.2 → NP_610025.1  nessun dorma, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610025.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NP13, Q9VIP0
      Related
      FBpp0080867

    2. NM_165320.2 → NP_724247.1  nessun dorma, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724247.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NP13, Q9VIP0
      Related
      FBpp0080866
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIP0.1 Q9VIP0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools