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    Nnf1b Nnf1b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318874, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Nnf1bprovided by FlyBase
    Official Full Name
    Nnf1bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051658
    Locus tag
    Dmel_CG31658
    See related
    AllianceGenome:FB:FBgn0051658
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31658; Dmel\CG31658; dmNnf1R-1
    Summary
    Involved in mitotic metaphase chromosome alignment. Located in kinetochore. Part of MIS12/MIND type complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Nnf1b in Genome Data Viewer
    Location:
    21E2-21E2; 2-1.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (810577..811531)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (810577..811531)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Protein kinase, cGMP-dependent at 21D Neighboring gene long non-coding RNA:CR45259 Neighboring gene DEAD box protein 21E2 Neighboring gene SAGA factor-like TAF6 Neighboring gene Peroxin 12 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Nnf1 paralogs are partially redundant for somatic and germ line kinetochore function. Blattner AC, et al. Chromosoma, 2017 Feb. PMID 26892014
    2. Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster. Liu Y, et al. Open Biol, 2016 Feb. PMID 26911624, Free PMC Article
    3. Network of protein interactions within the Drosophila inner kinetochore. Richter MM, et al. Open Biol, 2016 Feb. PMID 26911623, Free PMC Article
    4. Kinetochore Proteins Have a Post-Mitotic Function in Neurodevelopment. Zhao G, et al. Dev Cell, 2019 Mar 25. PMID 30827899, Free PMC Article
    5. Centromere structure and function: lessons from Drosophila. Kyriacou E, et al. Genetics, 2023 Dec 6. PMID 37931172, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromosome segregation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mitotic metaphase chromosome alignment IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MIS12/MIND type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in kinetochore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Nnf1b
    Names
    CG31658-PA
    Nnf1-related protein 1
    Nnf1b-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      810577..811531
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164388.3 → NP_722652.1  Nnf1b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722652.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPW3
      Related
      FBpp0077673
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IPW3 Q8IPW3

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