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    CG31668 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33395, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31668provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051668
    Locus tag
    Dmel_CG31668
    See related
    AllianceGenome:FB:FBgn0051668
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10879; CG31668-PB; Dmel\CG31668; dSLC5A12
    Summary
    Predicted to enable symporter activity. Predicted to be involved in sodium ion transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital hypothyroidism and thyroid dyshormonogenesis 1. Orthologous to human SLC5A12 (solute carrier family 5 member 12); SLC5A5 (solute carrier family 5 member 5); and SLC5A8 (solute carrier family 5 member 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31668 in Genome Data Viewer
    Location:
    22D1-22D4; 2-5 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2203721..2206166, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2203721..2206166, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44065 Neighboring gene uncharacterized protein Neighboring gene Cytochrome c oxidase subunit 7A-like 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Taste-independent nutrient selection is mediated by a brain-specific Na+ /solute co-transporter in Drosophila. Dus M, et al. Nat Neurosci, 2013 May. PMID 23542692, Free PMC Article
    2. Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. Rogers RL, et al. Genetics, 2009 Jan. PMID 19015547, Free PMC Article
    3. Chimeric genes as a source of rapid evolution in Drosophila melanogaster. Rogers RL, et al. Mol Biol Evol, 2012 Feb. PMID 21771717, Free PMC Article
    4. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
    5. Function-informed transcriptome analysis of Drosophila renal tubule. Wang J, et al. Genome Biol, 2004. PMID 15345053, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31668-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2203721..2206166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103585.3 → NP_001097055.2  uncharacterized protein Dmel_CG31668 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097055.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPY0, S5MXG6
      Conserved Domains (1) summary
      cd11492
      Location:9 → 531
      SLC5sbd_NIS-SMVT; Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IPY0 Q8IPY0

    Gene LinkOut

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