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    beg bad egg [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39910, updated on 9-Dec-2024

    Summary

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    Official Symbol
    begprovided by FlyBase
    Official Full Name
    bad eggprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036691
    Locus tag
    Dmel_CG7842
    See related
    AllianceGenome:FB:FBgn0036691
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7842; Dmel\CG7842
    Summary
    Predicted to enable [acyl-carrier-protein] S-malonyltransferase activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be active in mitochondrion. Is expressed in adult head. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human MCAT (malonyl-CoA-acyl carrier protein transacylase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See beg in Genome Data Viewer
    Location:
    73E4-73E5; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17035668..17036865)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17028768..17029965)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45756 Neighboring gene Insulin-like peptide 8 Neighboring gene long non-coding RNA:CR43250 Neighboring gene SR-related CTD associated factor 6 Neighboring gene PAPS transporter 2 Neighboring gene POP5 ribonuclease P/MRP subunit Neighboring gene Troponin C at 73F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a juvenile hormone response element and its binding proteins. Li Y, et al. J Biol Chem, 2007 Dec 28. PMID 17956872, Free PMC Article
    2. Conditional switches for extracellular matrix patterning in Drosophila melanogaster. Khokhar A, et al. Genetics, 2008 Mar. PMID 18245854, Free PMC Article
    3. Drosophila model for studying the link between lipid metabolism and development. Thanh MT, et al. Front Biosci (Landmark Ed), 2020 Jan 1. PMID 31585882
    4. Identification of sphingolipid metabolites that induce obesity via misregulation of appetite, caloric intake and fat storage in Drosophila. Walls SM Jr, et al. PLoS Genet, 2013. PMID 24339790, Free PMC Article
    5. Cdk8 attenuates lipogenesis by inhibiting SREBP-dependent transcription in Drosophila. Li X, et al. Dis Model Mech, 2022 Nov 1. PMID 36305265, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables [acyl-carrier-protein] S-malonyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables [acyl-carrier-protein] S-malonyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fatty acid biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    bad egg
    Names
    CG7842-PA
    beg-PA
    NP_648950.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17035668..17036865
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140693.3 → NP_648950.1  bad egg [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648950.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B6IDQ4, Q8T3L6, Q9VVD5
      Related
      FBpp0075038
      Conserved Domains (1) summary
      cl08282
      Location:63 → 377
      Acyl_transf_1; Acyl transferase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3L6.2 Q8T3L6

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