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    pcrH regulatory protein PcrH [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879267, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pcrH
    Gene description
    regulatory protein PcrH
    Locus tag
    PA1707
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1853181..1853684)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene type III secretion regulator Neighboring gene type III secretion protein PcrV Neighboring gene translocator protein PopB Neighboring gene translocator outer membrane protein PopD Neighboring gene exoenzyme S synthesis protein ExsC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Binding mode analysis of a major T3SS translocator protein PopB with its chaperone PcrH from Pseudomonas aeruginosa. Banerjee A, et al. Proteins, 2014 Dec. PMID 25116453
    2. Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa. Discola KF, et al. J Biol Chem, 2014 Feb 7. PMID 24297169, Free PMC Article
    3. PcrH of Pseudomonas aeruginosa is essential for secretion and assembly of the type III translocon. Bröms JE, et al. J Infect Dis, 2003 Dec 15. PMID 14673772
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within chaperone-mediated protein complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein secretion by the type III secretion system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulatory protein PcrH
    NP_250398.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1853181..1853684
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250398.1 regulatory protein PcrH [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250398.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9I325
      Conserved Domains (2) summary
      TIGR02552
      Location:20 → 153
      LcrH_SycD; type III secretion low calcium response chaperone LcrH/SycD
      sd00006
      Location:37 → 64
      TPR; TPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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