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    eIF2Bgamma eukaryotic translation initiation factor 2B subunit gamma [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1274918, updated on 22-Jun-2024

    Summary

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    Gene symbol
    eIF2Bgamma
    Gene description
    eukaryotic translation initiation factor 2B subunit gamma
    See related
    VectorBase:AGAMI1_002358
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Also known as
    AGAP005210
    Orthologs
    fruit fly all
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    Genomic context

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    See eIF2Bgamma in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (81247360..81249327)

    Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene SCY1-like protein bma Neighboring gene general odorant-binding protein 72-like Neighboring gene lethal (2) k01209 Neighboring gene threonylcarbamoyladenosine tRNA methylthiotransferase Neighboring gene DENN domain-containing protein 2D Neighboring gene unconventional myosin-XV

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones. Gomez SM, et al. Genome Biol, 2005. PMID 15833126, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytoplasmic translational initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of eukaryotic translation initiation factor 2B complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of guanyl-nucleotide exchange factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    translation initiation factor eIF-2B subunit gamma
    Names
    AGAP005210-PA

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      81247360..81249327
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_314112.5 → XP_314112.3  translation initiation factor eIF-2B subunit gamma

      See identical proteins and their annotated locations for XP_314112.3

      UniProtKB/TrEMBL
      Q7Q9J1
      Conserved Domains (3) summary
      cd04652
      Location:357 → 436
      LbH_eIF2B_gamma_C; eIF-2B gamma subunit, C-terminal Left-handed parallel beta-Helix (LbH) domain: eIF-2B is a eukaryotic translation initiator, a guanine nucleotide exchange factor (GEF) composed of five different subunits (alpha, beta, gamma, delta and epsilon). eIF2B is ...
      cd04198
      Location:6 → 217
      eIF-2B_gamma_N; The N-terminal domain of gamma subunit of the eIF-2B is a subfamily of glycosyltransferase 2
      COG1208
      Location:7 → 436
      GCD1; NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]
    Nucleotide Protein Strain
    Heading Accession and Version

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