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    putative hydroxyacid dehydrogenase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852690, updated on 9-Dec-2024

    Summary

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    Official Full Name
    putative hydroxyacid dehydrogenase
    Primary source
    SGD:S000003153
    Locus tag
    YGL185C
    See related
    AllianceGenome:SGD:S000003153; FungiDB:YGL185C; VEuPathDB:YGL185C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (153167..154306, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit IV Neighboring gene Tpn1p Neighboring gene cystathionine beta-lyase STR3 Neighboring gene Mnd1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ORF YNL274c (GOR1) codes for glyoxylate reductase in Saccharomyces cerevisiae. Rintala E, et al. Yeast, 2007 Feb. PMID 17173333
    2. Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. Albers E, et al. J Biol Chem, 2003 Mar 21. PMID 12525494
    3. Stereoselective, biocatalytic reductions of alpha-chloro-beta-keto esters. Kaluzna IA, et al. J Org Chem, 2005 Jan 7. PMID 15624945
    4. Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Fromont-Racine M, et al. Yeast, 2000 Jun 30. PMID 10900456, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. Tettelin H, et al. Nature, 1997 May 29. PMID 9169869

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glyoxylate reductase (NADPH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydroxypyruvate reductase [NAD(P)H] activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables phosphoglycerate dehydrogenase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative hydroxyacid dehydrogenase
    NP_011330.1
    • Putative protein with sequence similar to hydroxyacid dehydrogenases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      153167..154306 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181050.1 → NP_011330.1  TPA: putative hydroxyacid dehydrogenase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011330.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTW9, P53100
      UniProtKB/TrEMBL
      A6ZU03, B3LHN4, B5VIE6, C7GX09, C8Z867, N1PA04
      Conserved Domains (1) summary
      cd12168
      Location:10 → 367
      Mand_dh_like; D-Mandelate Dehydrogenase-like dehydrogenases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53100.1

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