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    pchF pyochelin synthetase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880083, updated on 11-Sep-2024

    Summary

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    Gene symbol
    pchF
    Gene description
    pyochelin synthetase
    Locus tag
    PA4225
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4731369..4736798, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Fe(III)-pyochelin outer membrane receptor Neighboring gene ABC transporter ATP-binding protein Neighboring gene ABC transporter ATP-binding protein Neighboring gene pyochelin biosynthetic protein PchG Neighboring gene dihydroaeruginoic acid synthetase Neighboring gene transcriptional regulator PchR Neighboring gene 2,3-dihydroxybenzoate-AMP ligase Neighboring gene pyochelin biosynthetic protein PchC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis. Ronnebaum TA, et al. Biochemistry, 2019 Feb 12. PMID 30525512, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    pyochelin synthetase
    NP_252915.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4731369..4736798 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252915.1 pyochelin synthetase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252915.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9RFM7
      Conserved Domains (6) summary
      PRK12467
      Location:1351 → 1747
      PRK12467; peptide synthase; Provisional
      cd12114
      Location:528 → 1010
      A_NRPS_TlmIV_like; The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes
      cd19535
      Location:69 → 490
      Cyc_NRPS; Cyc (heterocyclization) domain of nonribosomal peptide synthetases (NRPSs); belongs to the Condensation-domain family
      pfam08242
      Location:1162 → 1267
      Methyltransf_12; Methyltransferase domain
      pfam18563
      Location:5 → 53
      TubC_N; TubC N-terminal docking domain
      cl17068
      Location:1311 → 1389
      AFD_class_I; Adenylate forming domain, Class I superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HWG4.1

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