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    pvcB paerucumarin biosynthesis protein PvcB [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878457, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pvcB
    Gene description
    paerucumarin biosynthesis protein PvcB
    Locus tag
    PA2255
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (2483049..2483924)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene L-asparaginase I Neighboring gene paerucumarin biosynthesis protein PvcA Neighboring gene paerucumarin biosynthesis protein PvcC Neighboring gene paerucumarin biosynthesis protein PvcD Neighboring gene HTH-type transcriptional regulator PtxR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products. Zhu J, et al. Biochemistry, 2015 Apr 28. PMID 25866990
    2. Three-dimensional structures of Pseudomonas aeruginosa PvcA and PvcB, two proteins involved in the synthesis of 2-isocyano-6,7-dihydroxycoumarin. Drake EJ, et al. J Mol Biol, 2008 Dec 5. PMID 18824174, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The common pathway intermediate produced by PvcA is directed toward different ultimate products by PvcB, a member of the family of Fe(2+), alpha-ketoglutarate-dependent oxygenases.
      Title: Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products.
    2. The three-dimensional crystal structures of PvcA and PvcB, are determined.
      Title: Three-dimensional structures of Pseudomonas aeruginosa PvcA and PvcB, two proteins involved in the synthesis of 2-isocyano-6,7-dihydroxycoumarin.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    paerucumarin biosynthesis protein PvcB
    NP_250945.1
    • Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      2483049..2483924
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250945.1 paerucumarin biosynthesis protein PvcB [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250945.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      O30371
      Conserved Domains (1) summary
      COG2175
      Location:7 → 287
      TauD; Taurine dioxygenase, alpha-ketoglutarate-dependent [Secondary metabolites biosynthesis, transport and catabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I1L4.1

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