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    BNA3 kynurenine--oxoglutarate transaminase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853386, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BNA3
    Official Full Name
    kynurenine--oxoglutarate transaminase
    Primary source
    SGD:S000003596
    Locus tag
    YJL060W
    See related
    AllianceGenome:SGD:S000003596; FungiDB:YJL060W; VEuPathDB:YJL060W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables 2-aminoadipate transaminase activity and kynurenine-oxoglutarate transaminase activity. Involved in kynurenic acid biosynthetic process. Located in mitochondrion. Orthologous to several human genes including KYAT1 (kynurenine aminotransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See BNA3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (323386..324720)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene mannose-ethanolamine phosphotransferase LAS21 Neighboring gene linker nucleoporin NUP82 Neighboring gene amino acid transporter YHC3 Neighboring gene Bit61p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence. Wogulis M, et al. Biochemistry, 2008 Feb 12. PMID 18205391
    2. Alpha-complementation as a probe for dual localization of mitochondrial proteins. Karniely S, et al. Exp Cell Res, 2006 Nov 15. PMID 17034789
    3. The automation of science. King RD, et al. Science, 2009 Apr 3. PMID 19342587
    4. On the formalization and reuse of scientific research. King RD, et al. J R Soc Interface, 2011 Oct 7. PMID 21490004, Free PMC Article
    5. Genetic determinants of volatile-thiol release by Saccharomyces cerevisiae during wine fermentation. Howell KS, et al. Appl Environ Microbiol, 2005 Sep. PMID 16151133, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 2-aminoadipate transaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kynurenine-oxoglutarate transaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kynurenine-oxoglutarate transaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables kynurenine-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kynurenine-oxoglutarate transaminase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-kynurenine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in kynurenic acid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    kynurenine--oxoglutarate transaminase
    NP_012475.3
    • Kynurenine aminotransferase; catalyzes formation of kynurenic acid from kynurenine; potential Cdc28p substrate

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      323386..324720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181493.3 → NP_012475.3  TPA: kynurenine--oxoglutarate transaminase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012475.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWC2, P47039
      UniProtKB/TrEMBL
      A6ZPR3, B3LQ50, C7GR52, C8ZBF4, G2WGV6
      Conserved Domains (1) summary
      COG0436
      Location:54 → 444
      AspB; Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47039.1

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