Slc41a2 solute carrier family 41, member 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Slc41a2provided by MGI
Official Full Name: solute carrier family 41, member 2provided by MGI
Primary source: MGI:MGI:2442940
See related: Ensembl:ENSMUSG00000034591 AllianceGenome:MGI:2442940
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: SLC41A1-L1; A230035L05Rik
Summary: Enables inorganic cation transmembrane transporter activity. Involved in metal ion transport. Acts upstream of or within metal ion transport. Predicted to be active in plasma membrane. Is expressed in metanephros. Orthologous to human SLC41A2 (solute carrier family 41 member 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in genital fat pad adult (RPKM 8.4), large intestine adult (RPKM 4.3) and 22 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 C1; 10 41.03 cM

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (83066712..83174657, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (83230848..83338037, complement)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SLC41A2 is a Mg2+ transporter that might be involved in magnesium homeostasis in epithelial cells
Title: Functional characterization of the mouse [corrected] solute carrier, SLC41A2.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Markers

AI013202 (e-PCR)
- UniSTS:250189

Slc41a2 (e-PCR), detects polymorphism
- UniSTS:546011

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables inorganic cation transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables monoatomic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cobalt ion transport	IDA Inferred from Direct Assay more info	PubMed
involved_in iron ion transport	IDA Inferred from Direct Assay more info	PubMed
involved_in magnesium ion transport	IDA Inferred from Direct Assay more info	PubMed
involved_in magnesium ion transport	ISO Inferred from Sequence Orthology more info
involved_in manganese ion transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within metal ion transport	IDA Inferred from Direct Assay more info	PubMed
involved_in nickel cation transport	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: solute carrier family 41 member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.