Ccdc61 coiled-coil domain containing 61 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ccdc61provided by MGI
Official Full Name: coiled-coil domain containing 61provided by MGI
Primary source: MGI:MGI:2685005
See related: Ensembl:ENSMUSG00000074358 AllianceGenome:MGI:2685005
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm159; C530028I08Rik
Summary: Predicted to enable identical protein binding activity and microtubule binding activity. Predicted to be involved in centriole assembly and mitotic spindle assembly. Predicted to be located in centriolar satellite. Predicted to be part of centriolar subdistal appendage. Predicted to be active in ciliary basal body. Orthologous to human CCDC61 (coiled-coil domain containing 61). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 12.9), thymus adult (RPKM 11.6) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 A3; 7 9.38 cM

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (18624808..18644417, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (18890883..18910414, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISS Inferred from Sequence or Structural Similarity more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cell projection organization	IEA Inferred from Electronic Annotation more info
involved_in centriole assembly	ISO Inferred from Sequence Orthology more info
involved_in centriole assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitotic spindle assembly	ISO Inferred from Sequence Orthology more info
involved_in mitotic spindle assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
located_in centriolar satellite	ISS Inferred from Sequence or Structural Similarity more info
part_of centriolar subdistal appendage	ISO Inferred from Sequence Orthology more info
part_of centriolar subdistal appendage	ISS Inferred from Sequence or Structural Similarity more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in centrosome	ISS Inferred from Sequence or Structural Similarity more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
located_in ciliary basal body	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in microtubule organizing center	ISO Inferred from Sequence Orthology more info
located_in microtubule organizing center	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: centrosomal protein CCDC61

Names: VFL3 homolog; coiled-coil domain-containing protein 61

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033314.4 → NP_001028486.1 centrosomal protein CCDC61 isoform 1

See identical proteins and their annotated locations for NP_001028486.1

Status: VALIDATED

Source sequence(s)

AC153651

Consensus CDS

CCDS39791.1

UniProtKB/Swiss-Prot

Q3UJV1

Related

ENSMUSP00000096377.4, ENSMUST00000098780.10

Conserved Domains (1) summary

COG1196
Location:148 → 274

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
NM_001419239.1 → NP_001406168.1 centrosomal protein CCDC61 isoform 2

Status: VALIDATED

Source sequence(s)

AC153651
NM_001419240.1 → NP_001406169.1 centrosomal protein CCDC61 isoform 1

Status: VALIDATED

Source sequence(s)

AC153651

UniProtKB/Swiss-Prot

Q3UJV1
NM_001419241.1 → NP_001406170.1 centrosomal protein CCDC61 isoform 1

Status: VALIDATED

Source sequence(s)

AC153651

UniProtKB/Swiss-Prot

Q3UJV1
NM_001419242.1 → NP_001406171.1 centrosomal protein CCDC61 isoform 1

Status: VALIDATED

Source sequence(s)

AC153651

UniProtKB/Swiss-Prot

Q3UJV1
NM_001419244.1 → NP_001406173.1 centrosomal protein CCDC61 isoform 2

Status: VALIDATED

Source sequence(s)

AC153651
NM_001419245.1 → NP_001406174.1 centrosomal protein CCDC61 isoform 2

Status: VALIDATED

Source sequence(s)

AC153651
NM_001419246.1 → NP_001406175.1 centrosomal protein CCDC61 isoform 2

Status: VALIDATED

Source sequence(s)

AC153651
NM_001419247.1 → NP_001406176.1 centrosomal protein CCDC61 isoform 2

Status: VALIDATED

Source sequence(s)

AC153651

RNA

NR_185052.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC153651

Related

ENSMUST00000135467.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

18624808..18644417 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036152947.1 → XP_036008840.1 centrosomal protein CCDC61 isoform X3
XM_006539814.5 → XP_006539877.2 centrosomal protein CCDC61 isoform X2

See identical proteins and their annotated locations for XP_006539877.2

UniProtKB/Swiss-Prot

Q3UJV1

Conserved Domains (1) summary

COG1196
Location:148 → 274

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]