U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Speg striated muscle enriched protein kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363256, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Spegprovided by RGD
    Official Full Name
    striated muscle enriched protein kinaseprovided by RGD
    Primary source
    RGD:2124
    See related
    EnsemblRapid:ENSRNOG00000019850 AllianceGenome:RGD:2124
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Apeg1; APEG-1
    Summary
    Predicted to enable protein kinase activity. Involved in muscle cell differentiation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in centronuclear myopathy 5. Orthologous to human SPEG (striated muscle enriched protein kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 111.7), Heart (RPKM 75.3) and 6 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Speg in Genome Data Viewer
    Location:
    9q33
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (84314387..84371816)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (76865714..76923170)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (82571333..82628684)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene aspartyl aminopeptidase Neighboring gene uncharacterized LOC102550477 Neighboring gene desmin Neighboring gene uncharacterized LOC120094713 Neighboring gene uncharacterized LOC108351955 Neighboring gene GDP-mannose pyrophosphorylase A

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Striated muscle-specific serine/threonine-protein kinase beta segregates with high versus low responsiveness to endurance exercise training. Kusić D, et al. Physiol Genomics, 2020 Jan 1. PMID 31790338, Free PMC Article
    2. APEG-1, a novel gene preferentially expressed in aortic smooth muscle cells, is down-regulated by vascular injury. Hsieh CM, et al. J Biol Chem, 1996 Jul 19. PMID 8663449
    3. Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1. Hsieh CM, et al. J Biol Chem, 2000 Nov 24. PMID 10973969
    4. Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice. Liu X, et al. Circulation, 2009 Jan 20. PMID 19118250, Free PMC Article
    5. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Striated muscle-specific serine/threonine-protein kinase beta segregates with high versus low responsiveness to endurance exercise training.
      Title: Striated muscle-specific serine/threonine-protein kinase beta segregates with high versus low responsiveness to endurance exercise training.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 3-phosphoinositide-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables Rho-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables eukaryotic translation initiation factor 2alpha kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AS121 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AT120 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AXS139 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2BS14 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2BS36 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3S10 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3S28 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3S57 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3T11 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3T3 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3T45 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H3T6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H4S1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosomal protein S6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cardiac muscle cell development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within circulatory system development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in muscle cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in muscle cell differentiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in muscle structure development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within respiratory system development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    striated muscle-specific serine/threonine-protein kinase
    Names
    SPEG complex locus
    aortic preferentially expressed gene 1
    aortic preferentially expressed protein 1
    NP_001102272.1
    NP_037037.1
    XP_006245314.1
    XP_006245317.1
    XP_006245318.1
    XP_017452015.1
    XP_017452016.1
    XP_017452017.1
    XP_017452018.1
    XP_038939815.1
    XP_038939816.1
    XP_038939818.1
    XP_038939820.1
    XP_038939821.1
    XP_063123482.1
    XP_063123483.1
    XP_063123484.1
    XP_063123485.1
    XP_063123486.1
    XP_063123487.1
    XP_063123488.1
    XP_063123489.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108802.2 → NP_001102272.1  striated muscle-specific serine/threonine-protein kinase isoform 1

      See identical proteins and their annotated locations for NP_001102272.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/Swiss-Prot
      Q63638
      UniProtKB/TrEMBL
      A0A8I6ADG2, A6JW28
      Related
      ENSRNOP00000026941.4, ENSRNOT00000026941.9
      Conserved Domains (9) summary
      cd00096
      Location:62 → 124
      Ig; Immunoglobulin domain
      smart00408
      Location:1082 → 1148
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:1606 → 1859
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:727 → 816
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:1603 → 1859
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:817 → 873
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam17061
      Location:2787 → 2947
      PARM; PARM
      cl11960
      Location:750 → 809
      Ig; Immunoglobulin domain
      cl21453
      Location:2954 → 3210
      PKc_like; Protein Kinases, catalytic domain

    2. NM_012905.2 → NP_037037.1  striated muscle-specific serine/threonine-protein kinase isoform 4

      See identical proteins and their annotated locations for NP_037037.1

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (4) has multiple differences, compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant 1. The encoded protein (isoform 4) is shorter than isoform 1. This variant corresponds to the mouse APEG-1 variant described in PubMed ID: 10973969.
      Source sequence(s)
      BC087690, EV763588
      UniProtKB/TrEMBL
      A0A8L2QUK8, A6JW29
      Conserved Domains (2) summary
      smart00408
      Location:33 → 100
      IGc2; Immunoglobulin C-2 Type
      pfam07679
      Location:20 → 110
      I-set; Immunoglobulin I-set domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      84314387..84371816
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063267416.1 → XP_063123486.1  striated muscle-specific serine/threonine-protein kinase isoform X12

      UniProtKB/TrEMBL
      A0A8I5ZN28

    2. XM_039083887.2 → XP_038939815.1  striated muscle-specific serine/threonine-protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A8I6ADG2
      Conserved Domains (8) summary
      PHA03247
      Location:324 → 681
      PHA03247; large tegument protein UL36; Provisional
      cd14108
      Location:1613 → 1869
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:827 → 883
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:737 → 826
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:1079 → 1082
      Ig; Ig strand A [structural motif]
      cd20975
      Location:884 → 974
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:1079 → 1168
      Ig; Immunoglobulin domain
      cl21453
      Location:2964 → 3220
      PKc_like; Protein Kinases, catalytic domain

    3. XM_063267412.1 → XP_063123482.1  striated muscle-specific serine/threonine-protein kinase isoform X2

      UniProtKB/TrEMBL
      A0A8I6ADG2

    4. XM_039083888.2 → XP_038939816.1  striated muscle-specific serine/threonine-protein kinase isoform X3

      UniProtKB/TrEMBL
      A0A8I6ADG2
      Conserved Domains (8) summary
      PHA03247
      Location:265 → 622
      PHA03247; large tegument protein UL36; Provisional
      cd14108
      Location:1554 → 1810
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:768 → 824
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:678 → 767
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:1020 → 1023
      Ig; Ig strand A [structural motif]
      cd20975
      Location:825 → 915
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:1020 → 1109
      Ig; Immunoglobulin domain
      cl21453
      Location:2905 → 3161
      PKc_like; Protein Kinases, catalytic domain

    5. XM_039083892.2 → XP_038939820.1  striated muscle-specific serine/threonine-protein kinase isoform X8

      Conserved Domains (5) summary
      PHA03247
      Location:324 → 681
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:827 → 883
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:737 → 826
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:736 → 739
      Ig; Ig strand A [structural motif]
      cd20975
      Location:884 → 974
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains

    6. XM_039083893.2 → XP_038939821.1  striated muscle-specific serine/threonine-protein kinase isoform X9

      UniProtKB/TrEMBL
      A0A8I5ZN28
      Conserved Domains (5) summary
      PHA03247
      Location:324 → 681
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:827 → 883
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:737 → 826
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:736 → 739
      Ig; Ig strand A [structural motif]
      cd20975
      Location:884 → 974
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains

    7. XM_063267415.1 → XP_063123485.1  striated muscle-specific serine/threonine-protein kinase isoform X11

      UniProtKB/TrEMBL
      A0A8I5ZN28

    8. XM_063267417.1 → XP_063123487.1  striated muscle-specific serine/threonine-protein kinase isoform X13

    9. XM_006245252.5 → XP_006245314.1  striated muscle-specific serine/threonine-protein kinase isoform X6

      Conserved Domains (8) summary
      PHA03247
      Location:1206 → 1607
      PHA03247; large tegument protein UL36; Provisional
      cd14108
      Location:868 → 1124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:2219 → 2475
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82 → 138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755 → 844
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:334 → 337
      Ig; Ig strand A [structural motif]
      cd20975
      Location:139 → 229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:334 → 423
      Ig; Immunoglobulin domain

    10. XM_063267414.1 → XP_063123484.1  striated muscle-specific serine/threonine-protein kinase isoform X10

      UniProtKB/TrEMBL
      A0A8I5ZN28

    11. XM_063267418.1 → XP_063123488.1  striated muscle-specific serine/threonine-protein kinase isoform X14

      UniProtKB/TrEMBL
      A0A8I5ZN28
      Related
      ENSRNOP00000084140.2, ENSRNOT00000098450.2

    12. XM_063267419.1 → XP_063123489.1  striated muscle-specific serine/threonine-protein kinase isoform X15

      UniProtKB/TrEMBL
      A0A8I5ZN28

    13. XM_017596526.3 → XP_017452015.1  striated muscle-specific serine/threonine-protein kinase isoform X4

      UniProtKB/TrEMBL
      A0A8I6ADG2
      Conserved Domains (9) summary
      cd00096
      Location:933 → 1003
      Ig; Immunoglobulin domain
      smart00408
      Location:1025 → 1091
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:1549 → 1802
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:670 → 759
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:1546 → 1802
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:760 → 816
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam17061
      Location:2730 → 2890
      PARM; PARM
      cl11960
      Location:693 → 752
      Ig; Immunoglobulin domain
      cl21453
      Location:2897 → 3153
      PKc_like; Protein Kinases, catalytic domain

    14. XM_017596527.3 → XP_017452016.1  striated muscle-specific serine/threonine-protein kinase isoform X5

      UniProtKB/TrEMBL
      A0A8I6ADG2
      Related
      ENSRNOP00000105531.1, ENSRNOT00000122671.1

    15. XM_039083890.2 → XP_038939818.1  striated muscle-specific serine/threonine-protein kinase isoform X6

      Conserved Domains (8) summary
      PHA03247
      Location:1206 → 1607
      PHA03247; large tegument protein UL36; Provisional
      cd14108
      Location:868 → 1124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:2219 → 2475
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82 → 138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755 → 844
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:334 → 337
      Ig; Ig strand A [structural motif]
      cd20975
      Location:139 → 229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:334 → 423
      Ig; Immunoglobulin domain

    16. XM_017596529.2 → XP_017452018.1  striated muscle-specific serine/threonine-protein kinase isoform X6

      Conserved Domains (8) summary
      PHA03247
      Location:1206 → 1607
      PHA03247; large tegument protein UL36; Provisional
      cd14108
      Location:868 → 1124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:2219 → 2475
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82 → 138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755 → 844
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:334 → 337
      Ig; Ig strand A [structural motif]
      cd20975
      Location:139 → 229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:334 → 423
      Ig; Immunoglobulin domain

    17. XM_017596528.3 → XP_017452017.1  striated muscle-specific serine/threonine-protein kinase isoform X6

      Conserved Domains (8) summary
      PHA03247
      Location:1206 → 1607
      PHA03247; large tegument protein UL36; Provisional
      cd14108
      Location:868 → 1124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:2219 → 2475
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82 → 138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755 → 844
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:334 → 337
      Ig; Ig strand A [structural motif]
      cd20975
      Location:139 → 229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:334 → 423
      Ig; Immunoglobulin domain

    18. XM_063267413.1 → XP_063123483.1  striated muscle-specific serine/threonine-protein kinase isoform X6

    19. XM_006245255.5 → XP_006245317.1  striated muscle-specific serine/threonine-protein kinase isoform X7

      See identical proteins and their annotated locations for XP_006245317.1

      Conserved Domains (8) summary
      cd00096
      Location:136 → 206
      Ig; Immunoglobulin domain
      smart00408
      Location:228 → 294
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:752 → 1005
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:636 → 725
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:749 → 1005
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam17061
      Location:1933 → 2093
      PARM; PARM
      cl11960
      Location:356 → 428
      Ig; Immunoglobulin domain
      cl21453
      Location:2100 → 2356
      PKc_like; Protein Kinases, catalytic domain

    20. XM_006245256.5 → XP_006245318.1  striated muscle-specific serine/threonine-protein kinase isoform X7

      See identical proteins and their annotated locations for XP_006245318.1

      Conserved Domains (8) summary
      cd00096
      Location:136 → 206
      Ig; Immunoglobulin domain
      smart00408
      Location:228 → 294
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:752 → 1005
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:636 → 725
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:749 → 1005
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam17061
      Location:1933 → 2093
      PARM; PARM
      cl11960
      Location:356 → 428
      Ig; Immunoglobulin domain
      cl21453
      Location:2100 → 2356
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q63638.2 GenPept UniProtKB/Swiss-Prot:Q63638

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools