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    Garin5a golgi associated RAB2 interactor 5A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361564, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Garin5aprovided by RGD
    Official Full Name
    golgi associated RAB2 interactor 5Aprovided by RGD
    Primary source
    RGD:1311142
    See related
    EnsemblRapid:ENSRNOG00000031739 AllianceGenome:RGD:1311142
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam71e1; RGD1311142
    Summary
    Predicted to be involved in defense response to virus; innate immune response; and positive regulation of type I interferon production. Predicted to be located in Golgi apparatus. Orthologous to human GARIN5A (golgi associated RAB2 interactor 5A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 389.8), Testes (RPKM 222.4) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Garin5a in Genome Data Viewer
    Location:
    1q22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (104125477..104130543)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (94988959..94995971)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (100501556..100507334)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) 69 Neighboring gene ER membrane protein complex subunit 10 Neighboring gene myosin binding protein C2 Neighboring gene Spi-B transcription factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in defense response to virus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in innate immune response ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of type I interferon production ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    Golgi-associated RAB2 interactor protein 5A
    Names
    family with sequence similarity 71, member E1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001400842.1 → NP_001387771.1  Golgi-associated RAB2 interactor protein 5A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6A4X8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      104125477..104130543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063266601.1 → XP_063122671.1  Golgi-associated RAB2 interactor protein 5A isoform X4

      UniProtKB/TrEMBL
      A0A8I6A4X8
      Related
      ENSRNOP00000108146.1, ENSRNOT00000124332.1

    2. XM_063266615.1 → XP_063122685.1  Golgi-associated RAB2 interactor protein 5A isoform X9

      UniProtKB/TrEMBL
      A0A8I6A4X8

    3. XM_063266614.1 → XP_063122684.1  Golgi-associated RAB2 interactor protein 5A isoform X8

      UniProtKB/TrEMBL
      A0A8I6A4X8

    4. XM_006229179.5 → XP_006229241.1  Golgi-associated RAB2 interactor protein 5A isoform X3

      See identical proteins and their annotated locations for XP_006229241.1

      UniProtKB/TrEMBL
      A0A8I6A4X8, D4A176
      Related
      ENSRNOP00000045841.5, ENSRNOT00000043724.6
      Conserved Domains (1) summary
      pfam12480
      Location:93 → 158
      DUF3699; Protein of unknown function (DUF3699)

    5. XM_039100946.2 → XP_038956874.1  Golgi-associated RAB2 interactor protein 5A isoform X10

      Conserved Domains (1) summary
      pfam12480
      Location:33 → 92
      DUF3699; Protein of unknown function (DUF3699)

    6. XM_039100948.2 → XP_038956876.1  Golgi-associated RAB2 interactor protein 5A isoform X11

      Conserved Domains (1) summary
      pfam12480
      Location:2 → 61
      DUF3699; Protein of unknown function (DUF3699)

    7. XM_063266626.1 → XP_063122696.1  Golgi-associated RAB2 interactor protein 5A isoform X12

    8. XM_039100945.2 → XP_038956873.1  Golgi-associated RAB2 interactor protein 5A isoform X10

      Conserved Domains (1) summary
      pfam12480
      Location:33 → 92
      DUF3699; Protein of unknown function (DUF3699)

    9. XM_039100947.2 → XP_038956875.1  Golgi-associated RAB2 interactor protein 5A isoform X10

      Conserved Domains (1) summary
      pfam12480
      Location:33 → 92
      DUF3699; Protein of unknown function (DUF3699)

    10. XM_006229180.5 → XP_006229242.2  Golgi-associated RAB2 interactor protein 5A isoform X2

      Conserved Domains (1) summary
      pfam12480
      Location:118 → 177
      DUF3699; Protein of unknown function (DUF3699)

    11. XM_006229182.5 → XP_006229244.2  Golgi-associated RAB2 interactor protein 5A isoform X7

      UniProtKB/TrEMBL
      A0A8I6A4X8
      Conserved Domains (1) summary
      pfam12480
      Location:118 → 177
      DUF3699; Protein of unknown function (DUF3699)

    12. XM_039100941.2 → XP_038956869.1  Golgi-associated RAB2 interactor protein 5A isoform X1

      Conserved Domains (1) summary
      pfam12480
      Location:118 → 177
      DUF3699; Protein of unknown function (DUF3699)

    13. XM_039100942.2 → XP_038956870.1  Golgi-associated RAB2 interactor protein 5A isoform X5

      UniProtKB/TrEMBL
      A0A8I6A4X8, A6JAQ1
      Conserved Domains (1) summary
      pfam12480
      Location:118 → 177
      DUF3699; Protein of unknown function (DUF3699)

    14. XM_039100943.1 → XP_038956871.1  Golgi-associated RAB2 interactor protein 5A isoform X6

      UniProtKB/TrEMBL
      A0A8I6A4X8
      Conserved Domains (1) summary
      pfam12480
      Location:118 → 177
      DUF3699; Protein of unknown function (DUF3699)
    Nucleotide Protein Strain
    Heading Accession and Version

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