Tmem59l transmembrane protein 59-like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tmem59lprovided by MGI
Official Full Name: transmembrane protein 59-likeprovided by MGI
Primary source: MGI:MGI:1915187
See related: Ensembl:ENSMUSG00000035964 AllianceGenome:MGI:1915187
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 5330410G16Rik
Summary: Involved in branching involved in ureteric bud morphogenesis. Predicted to be located in Golgi membrane. Is expressed in several structures, including genitourinary system; liver; lung; nervous system; and retina. Orthologous to human TMEM59L (transmembrane protein 59 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in cerebellum adult (RPKM 122.7), cortex adult (RPKM 82.2) and 6 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 B3.3; 8 34.15 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (70936505..70939998, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (70483855..70487348, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2) 1 citation
Targeted (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in branching involved in ureteric bud morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: transmembrane protein 59-like

Names: brain-specific membrane-anchored protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001368366.1 → NP_001355295.1 transmembrane protein 59-like isoform 2 precursor

Status: VALIDATED

Source sequence(s)

AC157774
NM_001368367.1 → NP_001355296.1 transmembrane protein 59-like isoform 3 precursor

Status: VALIDATED

Source sequence(s)

AC157774
NM_182991.3 → NP_892036.1 transmembrane protein 59-like isoform 1 precursor

See identical proteins and their annotated locations for NP_892036.1

Status: VALIDATED

Source sequence(s)

AC157774

Consensus CDS

CCDS22368.1

UniProtKB/Swiss-Prot

Q7TNI2

Related

ENSMUSP00000043659.8, ENSMUST00000045286.9

Conserved Domains (1) summary

pfam12280
Location:72 → 278

BSMAP; Brain specific membrane anchored protein