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    CG10657 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39423, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10657provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036289
    Locus tag
    Dmel_CG10657
    See related
    AllianceGenome:FB:FBgn0036289
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD32330; Dmel\CG10657
    Summary
    Predicted to enable phosphatidylinositol bisphosphate binding activity. Predicted to be located in endosome. Is expressed in several structures, including adult head; dorsal head epidermis; embryonic anal pad; embryonic epipharynx; and gut section. Human ortholog(s) of this gene implicated in Bothnia retinal dystrophy; Newfoundland cone-rod dystrophy; fundus albipunctatus; night blindness; and retinitis pigmentosa. Orthologous to several human genes including CLVS2 (clavesin 2) and RLBP1 (retinaldehyde binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10657 in Genome Data Viewer
    Location:
    69C3-69C3; 3-38 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12491830..12497216, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12484930..12490316, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45681 Neighboring gene antisense RNA:CR45682 Neighboring gene antisense RNA:CR43868 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide transcriptional orchestration of circadian rhythms in Drosophila. Ueda HR, et al. J Biol Chem, 2002 Apr 19. PMID 11854264
    2. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Mummery-Widmer JL, et al. Nature, 2009 Apr 23. PMID 19363474, Free PMC Article
    3. Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease. Vartiainen S, et al. Dis Model Mech, 2014 Jun. PMID 24812436, Free PMC Article
    4. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
    5. Microarray analysis and organization of circadian gene expression in Drosophila. McDonald MJ, et al. Cell, 2001 Nov 30. PMID 11733057

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol bisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10657-PA
    retinaldehyde-binding related protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12491830..12497216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140322.3 → NP_648579.3  uncharacterized protein Dmel_CG10657 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648579.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RD7, Q9VTY1
      Related
      FBpp0075707
      Conserved Domains (2) summary
      smart01100
      Location:52 → 98
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:126 → 274
      CRAL_TRIO; CRAL/TRIO domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTY1 Q9VTY1

    Gene LinkOut

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