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    CG2765 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37994, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2765provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035087
    Locus tag
    Dmel_CG2765
    See related
    AllianceGenome:FB:FBgn0035087
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2765
    Summary
    Enables myosin binding activity. Predicted to be involved in regulation of lipid biosynthetic process. Predicted to be active in cytosol. Is expressed in several structures, including dorsal imaginal tissue; embryonic dorsal epidermis; embryonic/larval midgut; embryonic/larval oenocyte; and larval somatic muscle cell. Orthologous to several human genes including MID1IP1 (MID1 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2765 in Genome Data Viewer
    Location:
    60E10-60E11; 2-107 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24959841..24965076, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20847364..20852599, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44830 Neighboring gene cGAS-like receptor 2 Neighboring gene Ribosomal protein L19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cofilin regulator 14-3-3zeta is an evolutionarily conserved protein required for phagocytosis and microbial resistance. Ulvila J, et al. J Leukoc Biol, 2011 May. PMID 21208897
    2. Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargos. Liu R, et al. Development, 2008 Jan. PMID 18045836
    3. No accelerated rate of protein evolution in male-biased Drosophila pseudoobscura genes. Metta M, et al. Genetics, 2006 Sep. PMID 16816428, Free PMC Article
    4. Spatial and temporal control of gene expression in Drosophila using the inducible GeneSwitch GAL4 system. I. Screen for larval nervous system drivers. Nicholson L, et al. Genetics, 2008 Jan. PMID 18202369, Free PMC Article
    5. Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Ghosh AC, et al. Elife, 2020 Oct 27. PMID 33107824, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables myosin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of lipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2765-PC
    CG2765-PD
    CG2765-PE
    CG2765-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24959841..24965076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138144.3 → NP_611988.2  uncharacterized protein Dmel_CG2765, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611988.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYP4, Q7JRE5, Q9W0X5
      Conserved Domains (1) summary
      pfam07084
      Location:187 → 241
      Spot_14; Thyroid hormone-inducible hepatic protein Spot 14

    2. NM_001103982.3 → NP_001097452.1  uncharacterized protein Dmel_CG2765, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097452.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYP4, Q7JRE5, Q9W0X5
      Conserved Domains (1) summary
      pfam07084
      Location:187 → 241
      Spot_14; Thyroid hormone-inducible hepatic protein Spot 14

    3. NM_001103981.2 → NP_001097451.1  uncharacterized protein Dmel_CG2765, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097451.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYP4, Q7JRE5, Q9W0X5
      Conserved Domains (1) summary
      pfam07084
      Location:187 → 241
      Spot_14; Thyroid hormone-inducible hepatic protein Spot 14

    4. NM_001259586.2 → NP_001246515.1  uncharacterized protein Dmel_CG2765, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246515.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYP4, Q7JRE5, Q9W0X5
      Conserved Domains (1) summary
      pfam07084
      Location:187 → 241
      Spot_14; Thyroid hormone-inducible hepatic protein Spot 14
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JRE5 Q7JRE5
    Q9W0X5 Q9W0X5

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