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    chas chascon [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    chasprovided by FlyBase
    Official Full Name
    chasconprovided by FlyBase
    Primary source
    FLYBASE:FBgn0263258
    Locus tag
    Dmel_CG32556
    See related
    AllianceGenome:FB:FBgn0263258
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12987; CG12988; CG12989; CG32556; Chas; Dmel\CG32556; EP-631
    Summary
    Involved in establishment of body hair or bristle planar orientation. Located in apical plasma membrane and muscle tendon junction. Is expressed in several structures, including dorsal epidermis primordium; embryonic epipharynx; embryonic head epidermis; epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See chas in Genome Data Viewer
    Location:
    16B12-16C1; 1-58 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17672458..17698730, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17566491..17592763, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Integrator 2 Neighboring gene beta Spectrin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene par-6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Jitterbug/Filamin and Myosin-II form a complex in tendon cells required to maintain epithelial shape and polarity during musculoskeletal system development. Manieu C, et al. Mech Dev, 2018 Dec. PMID 30213743
    2. Establishment of the Muscle-Tendon Junction During Thorax Morphogenesis in Drosophila Requires the Rho-Kinase. Vega-Macaya F, et al. Genetics, 2016 Nov. PMID 27585845, Free PMC Article
    3. The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II. Carnesecchi J, et al. Nucleic Acids Res, 2022 Jan 25. PMID 34931250, Free PMC Article
    4. Tissue flow regulates planar cell polarity independently of the Frizzled core pathway. Ayukawa T, et al. Cell Rep, 2022 Sep 20. PMID 36130497
    5. Intertissue mechanical stress affects Frizzled-mediated planar cell polarity in the Drosophila notum epidermis. Olguín P, et al. Curr Biol, 2011 Feb 8. PMID 21276726, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in establishment of body hair or bristle planar orientation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in muscle tendon junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chascon
    Names
    CG32556-PA
    CG32556-PB
    CG32556-PC
    CG32556-PD
    CG32556-PE
    chas-PA
    chas-PB
    chas-PC
    chas-PD
    chas-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      17672458..17698730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167574.2 → NP_728092.1  chascon, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728092.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX26
      Related
      FBpp0074251

    2. NM_001298451.1 → NP_001285380.1  chascon, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285380.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX26

    3. NM_001298452.1 → NP_001285381.1  chascon, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285381.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JE77

    4. NM_206773.2 → NP_996496.1  chascon, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996496.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KUW6, Q8MT64

    5. NM_001298453.1 → NP_001285382.1  chascon, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285382.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KUW6, Q8MT64
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KUW6 Q7KUW6
    Q7YU70 Q7YU70
    Q8MT64 Q8MT64
    Q9VX26 Q9VX26
    X2JE77 X2JE77

    Gene LinkOut

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