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    CG3091 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31210, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3091provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029608
    Locus tag
    Dmel_CG3091
    See related
    AllianceGenome:FB:FBgn0029608
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3091
    Summary
    Predicted to enable phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Human ortholog(s) of this gene implicated in familial isolated deficiency of vitamin E. Orthologous to human TTPA (alpha tocopherol transfer protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3091 in Genome Data Viewer
    Location:
    2F2-2F2; 1-0.9 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2252332..2254197, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2146365..2148230, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene crooked neck Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene tempura

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative transcriptional profiling identifies takeout as a gene that regulates life span. Bauer J, et al. Aging (Albany NY), 2010 May. PMID 20519778, Free PMC Article
    2. Genome-wide transcription profile of field- and laboratory-selected dichlorodiphenyltrichloroethane (DDT)-resistant Drosophila. Pedra JH, et al. Proc Natl Acad Sci U S A, 2004 May 4. PMID 15118106, Free PMC Article
    3. Large-language models facilitate discovery of the molecular signatures regulating sleep and activity. Peng D, et al. Nat Commun, 2024 May 1. PMID 38693116, Free PMC Article
    4. Analysis of Ras-induced overproliferation in Drosophila hemocytes. Asha H, et al. Genetics, 2003 Jan. PMID 12586708, Free PMC Article
    5. Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells. Ramirez J, et al. PLoS One, 2015. PMID 26460970, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol bisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in intermembrane lipid transfer ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in late endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3091-PA
    CG3091-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2252332..2254197 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297887.1 → NP_001284816.1  uncharacterized protein Dmel_CG3091, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284816.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W503
      Conserved Domains (1) summary
      cd00170
      Location:101 → 262
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...

    2. NM_130634.4 → NP_569990.2  uncharacterized protein Dmel_CG3091, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569990.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W503
      Related
      FBpp0070400
      Conserved Domains (1) summary
      cd00170
      Location:101 → 262
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZ53 Q8SZ53
    Q9W503 Q9W503

    Gene LinkOut

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