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    bys by S6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31701, updated on 27-Dec-2024

    Summary

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    Official Symbol
    bysprovided by FlyBase
    Official Full Name
    by S6provided by FlyBase
    Primary source
    FLYBASE:FBgn0010292
    Locus tag
    Dmel_CG1430
    See related
    AllianceGenome:FB:FBgn0010292
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1430; Dmel\CG1430
    Summary
    Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Located in nucleus. Is expressed in several structures, including anterior endoderm; dorsal pharyngeal muscle primordium; embryonic/larval midgut primordium; gut section; and larval muscle cell. Orthologous to human BYSL (bystin like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See bys in Genome Data Viewer
    Location:
    7C2-7C2; 1-21 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7901880..7903643)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7795913..7797676)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Ribosomal protein S6 Neighboring gene defective proboscis extension response 14 Neighboring gene spidey

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Bys is nuclear and shows dynamic tissue-specific expression during development. Stewart MJ, et al. Dev Genes Evol, 2005 Feb. PMID 15580530
    2. The Drosophila ribosomal protein S6 gene includes a 3' triplication that arose by unequal crossing-over. Stewart MJ, et al. Mol Biol Evol, 1993 Sep. PMID 8412647
    3. Mutations in the Drosophila gene encoding ribosomal protein S6 cause tissue overgrowth. Stewart MJ, et al. Mol Cell Biol, 1993 Apr. PMID 8384310, Free PMC Article
    4. BEAF regulates cell-cycle genes through the controlled deposition of H3K9 methylation marks into its conserved dual-core binding sites. Emberly E, et al. PLoS Biol, 2008 Dec 23. PMID 19108610, Free PMC Article
    5. Drosophila nucleostemin 3 is required to maintain larval neuroblast proliferation. Johnson PW, et al. Dev Biol, 2018 Aug 1. PMID 29679561, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Bys protein is localized to the nucleus, suggesting that Drosophila Bys function may be conserved with that of yeast Enp1.
      Title: Drosophila Bys is nuclear and shows dynamic tissue-specific expression during development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    by S6
    Names
    CG1430-PA
    bys-PA
    bystin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7901880..7903643
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078519.3 → NP_511074.1  by S6 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_511074.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P51406, Q9W3N3
      Related
      FBpp0071046
      Conserved Domains (1) summary
      pfam05291
      Location:128 → 412
      Bystin; Bystin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P51406.2 P51406

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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