Ccdc113 coiled-coil domain containing 113 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ccdc113provided by MGI
Official Full Name: coiled-coil domain containing 113provided by MGI
Primary source: MGI:MGI:3606076
See related: Ensembl:ENSMUSG00000036598 AllianceGenome:MGI:3606076
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Cfap263; 4933409I22
Summary: Acts upstream of or within cilium assembly. Predicted to be located in centriolar satellite. Predicted to be part of protein-containing complex. Predicted to be active in axoneme and ciliary basal body. Is expressed in choroid invagination; lung; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human CFAP263 (cilia and flagella associated protein 263). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in testis adult (RPKM 24.6) and lung adult (RPKM 1.2) See more
Orthologs: human all
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Genomic context

Location:: 8 D1; 8 47.12 cM

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (96260684..96285516)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (95534060..95558888)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Ccdc113 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
Title: Tissue expression patterns identify mouse cilia genes.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

General gene information

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Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cilium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in axoneme	IBA Inferred from Biological aspect of Ancestor more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
located_in centriolar satellite	ISS Inferred from Sequence or Structural Similarity more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: cilia- and flagella-associated protein 263; coiled-coil domain-containing protein 113

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_172914.2 → NP_766502.1 cilia- and flagella-associated protein 263

See identical proteins and their annotated locations for NP_766502.1

Status: PROVISIONAL

Source sequence(s)

AK077130

Consensus CDS

CCDS22563.1

UniProtKB/Swiss-Prot

Q8C5T8

Related

ENSMUSP00000049497.4, ENSMUST00000041569.5

Conserved Domains (1) summary

pfam13870
Location:179 → 354

DUF4201; Domain of unknown function (DUF4201)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000074.7 Reference GRCm39 C57BL/6J

Range

96260684..96285516

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006531000.3 → XP_006531063.1 coiled-coil domain-containing protein 113 isoform X1

Conserved Domains (1) summary

cl00240
Location:95 → 165

RRF; Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another round of ...