Cep19 centrosomal protein 19 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cep19provided by MGI
Official Full Name: centrosomal protein 19provided by MGI
Primary source: MGI:MGI:1914244
See related: Ensembl:ENSMUSG00000035790 AllianceGenome:MGI:1914244
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1500031L02Rik
Summary: Predicted to be involved in microtubule anchoring at centrosome and vesicle targeting, trans-Golgi to periciliary membrane compartment. Predicted to be located in cilium and nucleoplasm. Predicted to be active in microtubule cytoskeleton. Is expressed in axial skeleton; lower jaw; and lower jaw incisor. Orthologous to human CEP19 (centrosomal protein 19). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in cortex adult (RPKM 13.3), frontal lobe adult (RPKM 12.9) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 16 B2; 16 22.4 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (31918618..31926875)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (32099789..32108068)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

loss of the ciliary protein CEP19 in humans and mice causes morbid obesity.
Title: Morbid obesity resulting from inactivation of the ciliary protein CEP19 in humans and mice.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (4) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI428934 (e-PCR)
- UniSTS:160556

RH125315 (e-PCR)
- UniSTS:162137

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in microtubule anchoring at centrosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule anchoring at centrosome	ISO Inferred from Sequence Orthology more info
involved_in microtubule anchoring at centrosome	ISS Inferred from Sequence or Structural Similarity more info
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment	ISO Inferred from Sequence Orthology more info
involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in centriole	IBA Inferred from Biological aspect of Ancestor more info
located_in centriole	ISO Inferred from Sequence Orthology more info
located_in centriole	ISS Inferred from Sequence or Structural Similarity more info
is_active_in centrosome	IBA Inferred from Biological aspect of Ancestor more info
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
located_in ciliary basal body	ISS Inferred from Sequence or Structural Similarity more info
located_in cilium	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in spindle pole	IBA Inferred from Biological aspect of Ancestor more info
located_in spindle pole	ISO Inferred from Sequence Orthology more info
located_in spindle pole	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: centrosomal protein of 19 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.