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    CG3699 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31046, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3699provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040349
    Locus tag
    Dmel_CG3699
    See related
    AllianceGenome:FB:FBgn0040349
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT12411; DECR2; Dmel\CG3699; EG:BACR7A4.14
    Summary
    Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity and testosterone 17-beta-dehydrogenase (NADP+) activity. Is expressed in Malpighian tubule primordium; adult head; adult heart; epithelium; and gut section. Orthologous to human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3699 in Genome Data Viewer
    Location:
    1D2-1D3; 1-0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (946662..947500, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (840695..841533, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mus81 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45476

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sleep and wakefulness modulate gene expression in Drosophila. Cirelli C, et al. J Neurochem, 2005 Sep. PMID 16001966
    2. The Genomic Basis of Postponed Senescence in Drosophila melanogaster. Carnes MU, et al. PLoS One, 2015. PMID 26378456, Free PMC Article
    3. Chronic low-dose γ-irradiation of Drosophila melanogaster larvae induces gene expression changes and enhances locomotive behavior. Kim CS, et al. J Radiat Res, 2015 May. PMID 25792464, Free PMC Article
    4. Fitness Analysis and Transcriptome Profiling Following Repeated Mild Heat Stress of Varying Frequency in Drosophilamelanogaster Females. Gruntenko NE, et al. Biology (Basel), 2021 Dec 14. PMID 34943239, Free PMC Article
    5. Absolute Quantification of Proteins in the Eye of Drosophila melanogaster. Raghuraman BK, et al. Proteomics, 2020 Dec. PMID 32663363

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables testosterone 17-beta-dehydrogenase (NADP+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3699-PA
    NP_569875.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      946662..947500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130519.3 → NP_569875.2  uncharacterized protein Dmel_CG3699 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569875.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BII6, Q9U1L2, Q9W5C0
      Related
      FBpp0070179
      Conserved Domains (2) summary
      PRK05653
      Location:1 → 244
      fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated
      cl21454
      Location:3 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BII6 Q5BII6
    Q8MSK8 Q8MSK8
    Q9U1L2 Q9U1L2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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