PGRP-SB1 Peptidoglycan recognition protein SB1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: PGRP-SB1provided by FlyBase
Official Full Name: Peptidoglycan recognition protein SB1provided by FlyBase
Primary source: FLYBASE:FBgn0043578
Locus tag: Dmel_CG9681
See related: AllianceGenome:FB:FBgn0043578
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 142657_at; CG9681; Dmel\CG9681; PGRP SB1; PGRP-SB
Summary: Enables N-acetylmuramoyl-L-alanine amidase activity. Predicted to be involved in defense response to bacterium; immune response; and peptidoglycan catabolic process. Located in extracellular region. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (16727299..16727989, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (16720399..16721089, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables N-acetylmuramoyl-L-alanine amidase activity	IDA Inferred from Direct Assay more info	PubMed
enables N-acetylmuramoyl-L-alanine amidase activity	IEA Inferred from Electronic Annotation more info
enables N-acetylmuramoyl-L-alanine amidase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables peptidoglycan binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in innate immune response	IEA Inferred from Electronic Annotation more info
involved_in innate immune response	NAS Non-traceable Author Statement more info	PubMed
involved_in peptidoglycan catabolic process	IEA Inferred from Electronic Annotation more info
involved_in peptidoglycan catabolic process	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in peptidoglycan catabolic process	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IDA Inferred from Direct Assay more info	PubMed

Names: CG9681-PA; PGRP-SB1-PA; Peptidoglycan-recognition protein-SB1 precursor; peptidoglycan receptor protein SB1; peptidoglycan recognition; protein-like

NP_648917.1

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The following sections contain reference sequences that belong to a specific genome build. Explain