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    MFS3 Major Facilitator Superfamily Transporter 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33292, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MFS3provided by FlyBase
    Official Full Name
    Major Facilitator Superfamily Transporter 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0031307
    Locus tag
    Dmel_CG4726
    See related
    AllianceGenome:FB:FBgn0031307
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4726; Dmel\CG4726; Mfs3
    Summary
    Enables D-glucose transmembrane transporter activity and trehalose transmembrane transporter activity. Involved in D-glucose transmembrane transport. Located in plasma membrane. Is expressed in several structures, including CNS glial cell; embryonic/larval midgut primordium; gut section; larval somatic muscle cell; and tracheal primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See MFS3 in Genome Data Viewer
    Location:
    21F1-21F1; 2-2 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1143201..1147395)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1143201..1147395)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 23 Neighboring gene iris Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45717 Neighboring gene lethal (2) 10685 Neighboring gene Transcription factor B4 Neighboring gene Vacuolar protein sorting 29 Neighboring gene capulet

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables D-glucose transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables trehalose transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-glucose transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    major facilitator superfamily transporter 3
    Names
    CG4726-PA
    MFS3-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1143201..1147395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134728.2 → NP_608572.1  major facilitator superfamily transporter 3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608572.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPX2
      Related
      FBpp0077623
      Conserved Domains (2) summary
      cd06174
      Location:100 → 479
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:19 → 489
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPX2 Q9VPX2

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