Ntl Neurotransmitter transporter-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Ntlprovided by FlyBase
Official Full Name: Neurotransmitter transporter-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0267326
Locus tag: Dmel_CG7075
See related: AllianceGenome:FB:FBgn0267326
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG7075; Dmel\CG7075; Mp; ntl; NTL
Summary: Enables glycine transmembrane transporter activity. Involved in flagellated sperm motility; glycine import across plasma membrane; and positive regulation of protein polyglycylation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult abdomen; adult head; and adult thorax. Orthologous to human SLC6A7 (solute carrier family 6 member 7). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (7710880..7713991)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (7710880..7713991)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables L-proline transmembrane transporter activity	ISM Inferred from Sequence Model more info	PubMed
enables amino acid:sodium symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables glycine transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables neurotransmitter transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in flagellated sperm motility	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glycine import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in glycine import across plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neurotransmitter transport	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of protein polyglycylation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proline transport	ISM Inferred from Sequence Model more info	PubMed
involved_in sodium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISM Inferred from Sequence Model more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain