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    CG13284 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35021, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13284provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032614
    Locus tag
    Dmel_CG13284
    See related
    AllianceGenome:FB:FBgn0032614
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13284
    Summary
    Predicted to enable oxidoreductase activity. Located in endoplasmic reticulum. Is expressed in several structures, including adult head; adult heart; embryonic anal pad; embryonic large intestine; and gut section. Orthologous to human HSDL1 (hydroxysteroid dehydrogenase like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13284 in Genome Data Viewer
    Location:
    36B2-36B2; 2-53 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16842300..16848716, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16842300..16848716, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Neprilysin-like 9 Neighboring gene Sarcolamban B Neighboring gene Sarcolamban A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conserved regulation of cardiac calcium uptake by peptides encoded in small open reading frames. Magny EG, et al. Science, 2013 Sep 6. PMID 23970561
    2. LncRNA mediated regulation of aging pathways in Drosophila melanogaster during dietary restriction. Yang D, et al. Aging (Albany NY), 2016 Sep 27. PMID 27687893, Free PMC Article
    3. GMAP is an Atg8a-interacting protein that regulates Golgi turnover in Drosophila. Rahman A, et al. Cell Rep, 2022 May 31. PMID 35649355, Free PMC Article
    4. Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. Kondylis V, et al. PLoS One, 2011 Feb 23. PMID 21383842, Free PMC Article
    5. Evolution of alternative splicing in newly evolved genes of Drosophila. Zhan Z, et al. Gene, 2011 Jan 1. PMID 20851753

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13284-PA
    CG13284-PB
    CG13284-PC
    CG13284-PD
    CG13284-PE
    NP_001260522.1
    NP_001260523.1
    NP_001285997.1
    NP_609816.1
    NP_724022.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      16842300..16848716 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299068.1 → NP_001285997.1  uncharacterized protein Dmel_CG13284, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285997.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86BQ3
      Conserved Domains (2) summary
      cd05356
      Location:56 → 295
      17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
      COG0300
      Location:56 → 309
      DltE; Short-chain dehydrogenase [General function prediction only]

    2. NM_001273594.1 → NP_001260523.1  uncharacterized protein Dmel_CG13284, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260523.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGQ3, Q9VJG9
      Conserved Domains (2) summary
      cd05356
      Location:70 → 309
      17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
      COG0300
      Location:70 → 323
      DltE; Short-chain dehydrogenase [General function prediction only]

    3. NM_135972.3 → NP_609816.1  uncharacterized protein Dmel_CG13284, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609816.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86BQ3
      Related
      FBpp0080480
      Conserved Domains (2) summary
      cd05356
      Location:56 → 295
      17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
      COG0300
      Location:56 → 309
      DltE; Short-chain dehydrogenase [General function prediction only]

    4. NM_001273593.1 → NP_001260522.1  uncharacterized protein Dmel_CG13284, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260522.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D5SHN1
      Conserved Domains (2) summary
      cd05356
      Location:69 → 308
      17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
      COG0300
      Location:69 → 322
      DltE; Short-chain dehydrogenase [General function prediction only]

    5. NM_165197.3 → NP_724022.2  uncharacterized protein Dmel_CG13284, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724022.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGQ3, Q9VJG9
      Related
      FBpp0080481
      Conserved Domains (2) summary
      cd05356
      Location:70 → 309
      17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
      COG0300
      Location:70 → 323
      DltE; Short-chain dehydrogenase [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D5SHN1 D5SHN1
    Q86BQ3 Q86BQ3
    Q8IGQ3 Q8IGQ3

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