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    Ugt37A1 UDP-glycosyltransferase family 37 member A1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35307, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ugt37A1provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 37 member A1provided by FlyBase
    Primary source
    FLYBASE:FBgn0026756
    Locus tag
    Dmel_CG11012
    See related
    AllianceGenome:FB:FBgn0026756
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    38C.41; CG11012; Dmel\CG11012; DmeUgt37a1; DmUgt37a1; Ugt37a1; UGT37A1
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human UGT1A6 (UDP glucuronosyltransferase family 1 member A6) and UGT2A3 (UDP glucuronosyltransferase family 2 member A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ugt37A1 in Genome Data Viewer
    Location:
    38C5-38C5; 2-54 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20372409..20374104, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20372409..20374083, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Rho-type guanine nucleotide exchange factor Neighboring gene La autoantigen-like Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Preferential expression of biotransformation enzymes in the olfactory organs of Drosophila melanogaster, the antennae. Wang Q, et al. J Biol Chem, 1999 Apr 9. PMID 10187818
    2. Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix. Parnas D, et al. Neuron, 2001 Nov 8. PMID 11709153
    3. Auxin exposure disrupts feeding behavior and fatty acid metabolism in adult Drosophila. Fleck SA, et al. Elife, 2024 Jan 19. PMID 38240746, Free PMC Article
    4. Endurance exercise and selective breeding for longevity extend Drosophila healthspan by overlapping mechanisms. Sujkowski A, et al. Aging (Albany NY), 2015 Aug. PMID 26298685, Free PMC Article
    5. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glycosyltransferase family 37 member A1
    Names
    CG11012-PB
    UDP-glycosyltransferase 37a1
    Ugt37A1-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20372409..20374104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078883.3 → NP_523607.2  UDP-glycosyltransferase family 37 member A1 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIM9
      Conserved Domains (1) summary
      cd03784
      Location:25 → 456
      GT1_Gtf-like; UDP-glycosyltransferases and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIM9 Q9VIM9

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