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    Tim13 Tim13 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39327, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tim13provided by FlyBase
    Official Full Name
    Tim13provided by FlyBase
    Primary source
    FLYBASE:FBgn0036204
    Locus tag
    Dmel_CG11611
    See related
    AllianceGenome:FB:FBgn0036204
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11611; Dmel\CG11611
    Summary
    Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to be part of mitochondrial intermembrane space protein transporter complex. Orthologous to human TIMM13 (translocase of inner mitochondrial membrane 13). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tim13 in Genome Data Viewer
    Location:
    68D4-68D4; 3-36 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11774060..11774501, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11767160..11767601, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene mir-314 stem loop Neighboring gene mir-956 stem loop Neighboring gene Phosphatidylinositol 3-kinase 68D Neighboring gene uncharacterized protein Neighboring gene twitchy

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PINK1 and Parkin control localized translation of respiratory chain component mRNAs on mitochondria outer membrane. Gehrke S, et al. Cell Metab, 2015 Jan 6. PMID 25565208, Free PMC Article
    2. Fast and effective prediction of microRNA/target duplexes. Rehmsmeier M, et al. RNA, 2004 Oct. PMID 15383676, Free PMC Article
    3. Genomic signatures of globally enhanced gene duplicate accumulation in the megadiverse higher Diptera fueling intralocus sexual conflict resolution. Bao R, et al. PeerJ, 2020. PMID 33083121, Free PMC Article
    4. The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication. Zhang Y, et al. EMBO J, 2016 May 17. PMID 27053724, Free PMC Article
    5. Parent genes of retrotransposition-generated gene duplicates in Drosophila melanogaster have distinct expression profiles. Langille MG, et al. Genomics, 2007 Sep. PMID 17628393

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein insertion into mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein insertion into mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial intermembrane space protein transporter complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial intermembrane space protein transporter complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Tim13
    Names
    CG11611-PA
    Tim13-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11774060..11774501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140248.2 → NP_648505.1  Tim13 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648505.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3DMW4, Q9VTN3
      UniProtKB/TrEMBL
      A0A1B2AK53
      Related
      FBpp0075820
      Conserved Domains (1) summary
      pfam02953
      Location:13 → 73
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTN3.1 Q9VTN3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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