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    CG14671 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40671, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14671provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037340
    Locus tag
    Dmel_CG14671
    See related
    AllianceGenome:FB:FBgn0037340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14671
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in vacuolar proton-transporting V-type ATPase complex assembly. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIo. Orthologous to human CCDC115 (coiled-coil domain containing 115). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14671 in Genome Data Viewer
    Location:
    83B2-83B2; 3-47.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5563977..5564815, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1389699..1390537, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol 4-kinase II alpha Neighboring gene ncRNA Neighboring gene antisense RNA:CR46136 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Type II phosphatidylinositol 4-kinase regulates nerve terminal growth and synaptic vesicle recycling. Cantarutti KC, et al. J Neurogenet, 2018 Sep. PMID 30175671
    2. Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila. Burgess J, et al. Development, 2012 Aug. PMID 22791894, Free PMC Article
    3. Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED. Hadžić T, et al. Nucleic Acids Res, 2015 Feb 27. PMID 25634895, Free PMC Article
    4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in vacuolar proton-transporting V-type ATPase complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14671-PA
    CG14671-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5563977..5564815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275359.1 → NP_001262288.1  uncharacterized protein Dmel_CG14671, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262288.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPV1, Q9VND4

    2. NM_141293.2 → NP_649550.1  uncharacterized protein Dmel_CG14671, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649550.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPV1, Q9VND4
      Related
      FBpp0078403
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VND4 Q9VND4

    Gene LinkOut

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