U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    jbug jitterbug [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43997, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    jbugprovided by FlyBase
    Official Full Name
    jitterbugprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028371
    Locus tag
    Dmel_CG30092
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AAF46896; CG11605; CG13525; CG30092; CG3550; Dmel\CG30092; Jbug
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See jbug in Genome Data Viewer
    Location:
    59A3-59A3; 2-101 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22717321..22740459, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18604826..18627964, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43735 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR30267 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development. Chung S, et al. Genetics, 2021 Oct 2. PMID 34173831, Free PMC Article
    2. Jitterbug/Filamin and Myosin-II form a complex in tendon cells required to maintain epithelial shape and polarity during musculoskeletal system development. Manieu C, et al. Mech Dev, 2018 Dec. PMID 30213743
    3. Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and multiple genes involved in axon guidance in Drosophila. Oliva C, et al. Dev Neurobiol, 2015 Sep. PMID 25652545
    4. Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila. Hekmat-Scafe DS, et al. J Neurosci, 2006 Aug 30. PMID 16943550, Free PMC Article
    5. Intertissue mechanical stress affects Frizzled-mediated planar cell polarity in the Drosophila notum epidermis. Olguín P, et al. Curr Biol, 2011 Feb 8. PMID 21276726, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development.
      Title: Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    jitterbug
    Names
    CG30092-PC
    CG30092-PF
    CG30092-PG
    CG30092-PH
    CG30092-PI
    CG30092-PJ
    CG30092-PK
    CG30092-PL
    CG30092-PM
    CG30092-PN
    filamin
    jbug-PC
    jbug-PF
    jbug-PG
    jbug-PH
    jbug-PI
    jbug-PJ
    jbug-PK
    jbug-PL
    jbug-PM
    jbug-PN

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22717321..22740459 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274210.1 → NP_001261139.1  jitterbug, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261139.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEX6
      Conserved Domains (5) summary
      smart00557
      Location:2734 → 2828
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:60 → 165
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00307
      Location:172 → 269
      CH; Calponin homology (CH) domain
      pfam00630
      Location:2731 → 2821
      Filamin; Filamin/ABP280 repeat
      pfam17069
      Location:639 → 918
      RSRP; Arginine/Serine-Rich protein 1

    2. NM_001274211.1 → NP_001261140.1  jitterbug, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261140.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFF9
      Conserved Domains (4) summary
      smart00557
      Location:2850 → 2944
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:60 → 165
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00307
      Location:172 → 269
      CH; Calponin homology (CH) domain
      pfam00630
      Location:2847 → 2937
      Filamin; Filamin/ABP280 repeat

    3. NM_166546.3 → NP_726234.3  jitterbug, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726234.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W205
      Conserved Domains (4) summary
      smart00557
      Location:2850 → 2944
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:60 → 165
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00307
      Location:172 → 269
      CH; Calponin homology (CH) domain
      pfam00630
      Location:2847 → 2937
      Filamin; Filamin/ABP280 repeat

    4. NM_001169787.2 → NP_001163258.1  jitterbug, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163258.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JGS7
      Conserved Domains (2) summary
      smart00557
      Location:1647 → 1741
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00630
      Location:1644 → 1734
      Filamin; Filamin/ABP280 repeat

    5. NM_166547.2 → NP_726235.2  jitterbug, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726235.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q058S6, Q9W204
      Conserved Domains (4) summary
      smart00557
      Location:1480 → 1569
      IG_FLMN; Filamin-type immunoglobulin domains
      cd00014
      Location:60 → 165
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam00307
      Location:172 → 269
      CH; Calponin homology (CH) domain
      pfam00630
      Location:1477 → 1563
      Filamin; Filamin/ABP280 repeat

    6. NM_001169786.2 → NP_001163257.1  jitterbug, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163257.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWQ7, Q8MME5
      Conserved Domains (2) summary
      smart00557
      Location:277 → 366
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00630
      Location:274 → 360
      Filamin; Filamin/ABP280 repeat

    7. NM_166550.3 → NP_726238.1  jitterbug, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726238.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWQ7, Q8MME5
      Related
      FBpp0071830
      Conserved Domains (2) summary
      smart00557
      Location:277 → 366
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00630
      Location:274 → 360
      Filamin; Filamin/ABP280 repeat

    8. NM_001169789.2 → NP_001163260.1  jitterbug, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163260.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWQ7, Q8MME5
      Conserved Domains (2) summary
      smart00557
      Location:277 → 366
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00630
      Location:274 → 360
      Filamin; Filamin/ABP280 repeat

    9. NM_001169785.2 → NP_001163256.1  jitterbug, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163256.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWQ7, Q8MME5
      Conserved Domains (2) summary
      smart00557
      Location:277 → 366
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00630
      Location:274 → 360
      Filamin; Filamin/ABP280 repeat

    10. NM_001169788.2 → NP_001163259.1  jitterbug, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163259.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWQ7, Q8MME5
      Conserved Domains (2) summary
      smart00557
      Location:277 → 366
      IG_FLMN; Filamin-type immunoglobulin domains
      pfam00630
      Location:274 → 360
      Filamin; Filamin/ABP280 repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KEX6 A0A0B4KEX6
    A0A0B4KFF9 A0A0B4KFF9
    E1JGS7 E1JGS7
    Q8MME5 Q8MME5
    Q95U66 Q95U66
    Q961W2 Q961W2
    Q9W204 Q9W204
    Q9W205 Q9W205

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools