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    CG15012 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38529, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15012provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035528
    Locus tag
    Dmel_CG15012
    See related
    AllianceGenome:FB:FBgn0035528
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15012
    Summary
    Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Is expressed in several structures, including adult head; adult heart; central brain primordium; ganglia; and larval imaginal tissue. Orthologous to human TMEM50A (transmembrane protein 50A) and TMEM50B (transmembrane protein 50B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15012 in Genome Data Viewer
    Location:
    64A12-64A12; 3-10 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4291208..4292246, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4291208..4292246, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Transcription factor IIEbeta Neighboring gene Hexosaminidase 1 Neighboring gene Ferredoxin 2 Neighboring gene dusky-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and characterization of the plasma membrane glycosidases of Drosophila melanogaster spermatozoa. Cattaneo F, et al. Insect Biochem Mol Biol, 2002 Aug. PMID 12110300
    2. Sex Differences in Drosophila Somatic Gene Expression: Variation and Regulation by doublesex. Arbeitman MN, et al. G3 (Bethesda), 2016 Jul 7. PMID 27172187, Free PMC Article
    3. Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Dutta D, et al. Proc Natl Acad Sci U S A, 2024 Feb 27. PMID 38381787, Free PMC Article
    4. New components of Drosophila leg development identified through genome wide association studies. Grubbs N, et al. PLoS One, 2013. PMID 23560084, Free PMC Article
    5. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in late endosome to vacuole transport via multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15012-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4291208..4292246 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169876.2 → NP_001163347.1  uncharacterized protein Dmel_CG15012 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163347.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZE2
      Conserved Domains (1) summary
      pfam05255
      Location:9 → 150
      UPF0220; uncharacterized protein family (UPF0220)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZE2 Q9VZE2

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