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    mRRF1 mitochondrial ribosome recycling factor 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39067, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mRRF1provided by FlyBase
    Official Full Name
    mitochondrial ribosome recycling factor 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0035980
    Locus tag
    Dmel_CG4447
    See related
    AllianceGenome:FB:FBgn0035980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4447; Dmel\CG4447
    Summary
    Predicted to enable ribosomal large subunit binding activity. Predicted to be involved in mitochondrial translation. Predicted to be active in mitochondrion. Is expressed in adult head and adult heart. Orthologous to human MRRF (mitochondrial ribosome recycling factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mRRF1 in Genome Data Viewer
    Location:
    67B2-67B2; 3-29 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9364350..9365240)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9357450..9358340)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Pyridoxal kinase Neighboring gene uncharacterized protein Neighboring gene Kinesin-like protein at 67A Neighboring gene uncharacterized protein Neighboring gene Ferredoxin 1 Neighboring gene Heat shock gene 67Bc

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The translation factors of Drosophila melanogaster. Marygold SJ, et al. Fly (Austin), 2017 Jan 2. PMID 27494710, Free PMC Article
    2. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624
    3. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
    4. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article
    5. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ribosomal large subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial ribosome recycling factor 1
    Names
    CG4447-PA
    mRRF1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9364350..9365240
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140045.3 → NP_648302.2  mitochondrial ribosome recycling factor 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648302.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0M6, Q9VSW4
      Related
      FBpp0076172
      Conserved Domains (1) summary
      cd00520
      Location:76 → 252
      RRF; Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another round of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T0M6 Q8T0M6
    Q9VSW4 Q9VSW4

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