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    CG15629 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33679, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15629provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031630
    Locus tag
    Dmel_CG15629
    See related
    AllianceGenome:FB:FBgn0031630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15629
    Summary
    Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity. Predicted to be active in lipid droplet. Is expressed in adult fat body; adult head; embryonic anal pad; and embryonic large intestine. Orthologous to several human genes including SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15629 in Genome Data Viewer
    Location:
    25A6-25A6; 2-13 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4813009..4815891)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4813009..4815891)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene schlaff Neighboring gene long non-coding RNA:CR45297 Neighboring gene uncharacterized protein Neighboring gene mir-4910 stem loop Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity. Butzlaff M, et al. Hum Mol Genet, 2015 Jul 1. PMID 25794683
    2. Toll mediated infection response is altered by gravity and spaceflight in Drosophila. Taylor K, et al. PLoS One, 2014. PMID 24475130, Free PMC Article
    3. The circadian clock interacts with metabolic physiology to influence reproductive fitness. Xu K, et al. Cell Metab, 2011 Jun 8. PMID 21641546, Free PMC Article
    4. Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus. Lu HL, et al. Sci Rep, 2015 Jul 23. PMID 26202798, Free PMC Article
    5. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables all-trans-retinol dehydrogenase (NAD+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15629-PA
    NP_608859.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4813009..4815891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135015.2 → NP_608859.1  uncharacterized protein Dmel_CG15629 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608859.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VR28
      Related
      FBpp0077075
      Conserved Domains (1) summary
      cd05339
      Location:58 → 298
      17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VR28 Q9VR28

    Gene LinkOut

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