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    Kebab Kinetochore and EB1 associated basic protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 48440, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Kebabprovided by FlyBase
    Official Full Name
    Kinetochore and EB1 associated basic proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028952
    Locus tag
    Dmel_CG31672
    See related
    AllianceGenome:FB:FBgn0028952
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD15963; CG31672; CG4248; Dmel\CG31672; keb; kebab; n(2)k09932
    Summary
    Enables kinetochore binding activity and microtubule binding activity. Located in kinetochore; perinuclear region of cytoplasm; and spindle microtubule. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Kebab in Genome Data Viewer
    Location:
    22C1-22C1; 2-4 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2045494..2048054)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2045494..2048054)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45298 Neighboring gene Suppressor of deltex Neighboring gene Odorant receptor 22c Neighboring gene defective proboscis extension response 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Kebab: kinetochore and EB1 associated basic protein that dynamically changes its localisation during Drosophila mitosis. Meireles AM, et al. PLoS One, 2011. PMID 21912673, Free PMC Article
    2. The exon junction complex differentially marks spliced junctions. Saulière J, et al. Nat Struct Mol Biol, 2010 Oct. PMID 20818392
    3. Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster. Kučerová L, et al. BMC Genomics, 2016 Jan 13. PMID 26758761, Free PMC Article
    4. Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge. Fukuyama H, et al. Proc Natl Acad Sci U S A, 2013 Jun 25. PMID 23749869, Free PMC Article
    5. The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. Spradling AC, et al. Genetics, 1999 Sep. PMID 10471706, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the identification of a novel Drosophila protein
      Title: Kebab: kinetochore and EB1 associated basic protein that dynamically changes its localisation during Drosophila mitosis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables kinetochore binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in spindle microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kinetochore and EB1 associated basic protein
    Names
    CG31672-PA
    CG31672-PB
    Kebab-PA
    Kebab-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2045494..2048054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164451.2 → NP_722756.1  kinetochore and EB1 associated basic protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722756.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F0JAI6
      Related
      FBpp0077498
      Conserved Domains (1) summary
      pfam11725
      Location:77 → 307
      AvrE; Pathogenicity factor

    2. NM_001272971.1 → NP_001259900.1  kinetochore and EB1 associated basic protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259900.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F0JAI6, Q961C7, Q9VQ69
      Conserved Domains (1) summary
      pfam11725
      Location:77 → 308
      AvrE; Pathogenicity factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F0JAI6.1 F0JAI6

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