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    Arp8 Actin-related protein 8 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32769, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Arp8provided by FlyBase
    Official Full Name
    Actin-related protein 8provided by FlyBase
    Primary source
    FLYBASE:FBgn0030877
    Locus tag
    Dmel_CG7846
    See related
    AllianceGenome:FB:FBgn0030877
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    arp8; CG7846; dArp8; Dmel\CG7846
    Summary
    Involved in regulation of DNA-templated transcription. Located in nucleus. Part of Ino80 complex. Is expressed in organism. Orthologous to human ACTR8 (actin related protein 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Arp8 in Genome Data Viewer
    Location:
    16E2-16E2; 1-59 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17858379..17860800, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17752412..17754833, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43981 Neighboring gene Multicopper oxidase 4 Neighboring gene Sulfiredoxin Neighboring gene uncharacterized protein Neighboring gene minibrain Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Burst of Genetic Innovation in Drosophila Actin-Related Proteins for Testis-Specific Function. Schroeder CM, et al. Mol Biol Evol, 2020 Mar 1. PMID 31697328, Free PMC Article
    2. A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Klymenko T, et al. Genes Dev, 2006 May 1. PMID 16618800, Free PMC Article
    3. The biology of chromatin remodeling complexes. Clapier CR, et al. Annu Rev Biochem, 2009. PMID 19355820
    4. Population distribution analyses reveal a hierarchy of molecular players underlying parallel endocytic pathways. Gupta GD, et al. PLoS One, 2014. PMID 24971745, Free PMC Article
    5. Correlation between desiccation stress response and epigenetic modifications of genes in Drosophila melanogaster: An example of environment-epigenome interaction. Sharma V, et al. Biochim Biophys Acta Gene Regul Mech, 2017 Oct. PMID 28801151

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in chromatin remodeling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in double-strand break repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ino80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Ino80 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Actin-related protein 8
    Names
    Arp8-PA
    CG7846-PA
    actin related protein 8

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      17858379..17860800 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_133023.4 → NP_573251.1  Actin-related protein 8 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573251.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VX09
      Related
      FBpp0074318
      Conserved Domains (1) summary
      cl17037
      Location:202 → 603
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VX09.1 Q9VX09

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