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    CG3631 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41797, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3631provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038268
    Locus tag
    Dmel_CG3631
    See related
    AllianceGenome:FB:FBgn0038268
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3631
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in proteoglycan biosynthetic process. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in adult fat body and spermatozoon. Orthologous to human FAM20B (FAM20B glycosaminoglycan xylosylkinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3631 in Genome Data Viewer
    Location:
    88D6-88D6; 3-56 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14879457..14882631)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10705179..10708353)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene bitesize Neighboring gene long non-coding RNA:CR46024 Neighboring gene uncharacterized protein Neighboring gene Rrp6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cyclin C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. Ishikawa HO, et al. PLoS One, 2012. PMID 22900076, Free PMC Article
    2. LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans. Tan S, et al. Genome Res, 2016 Dec. PMID 27934698, Free PMC Article
    3. TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster. Nakamura R, et al. Mol Cell Biol, 2008 Nov. PMID 18765642, Free PMC Article
    4. Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster. Schrider DR, et al. Genome Res, 2011 Dec. PMID 22135405, Free PMC Article
    5. The circadian clock interacts with metabolic physiology to influence reproductive fitness. Xu K, et al. Cell Metab, 2011 Jun 8. PMID 21641546, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphotransferase activity, alcohol group as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteoglycan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3631-PC
    CG3631-PD
    CG3631-PE
    NP_650398.3
    NP_731951.2
    NP_996212.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14879457..14882631
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206490.3 → NP_996212.1  uncharacterized protein Dmel_CG3631, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996212.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95T10
      Conserved Domains (1) summary
      cl05973
      Location:224 → 414
      FAM20_C_like; C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins

    2. NM_142141.3 → NP_650398.3  uncharacterized protein Dmel_CG3631, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650398.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95T10
      Conserved Domains (1) summary
      cl05973
      Location:224 → 414
      FAM20_C_like; C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins

    3. NM_169605.3 → NP_731951.2  uncharacterized protein Dmel_CG3631, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731951.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95T10
      Conserved Domains (1) summary
      cl05973
      Location:224 → 414
      FAM20_C_like; C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95T10.1 Q95T10

    Gene LinkOut

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