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    Golgin97 Golgin 97 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36492, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Golgin97provided by FlyBase
    Official Full Name
    Golgin 97provided by FlyBase
    Primary source
    FLYBASE:FBgn0086757
    Locus tag
    Dmel_CG4840
    See related
    AllianceGenome:FB:FBgn0086757
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cbs; Cbs; CG4840; dem; dGolgin-97; dGolgin97; Dmel\CG4840
    Summary
    Enables small GTPase binding activity. Involved in centrosome cycle. Located in several cellular components, including Golgi trans cisterna; perinuclear region of cytoplasm; and spindle. Orthologous to human GOLGA1 (golgin A1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Golgin97 in Genome Data Viewer
    Location:
    50A9-50A9; 2-68 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13450586..13453393)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9338091..9340898)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene ATPase 8A Neighboring gene transfer RNA:Isoleucine-AAT 1-8 Neighboring gene centrosomin Neighboring gene uncharacterized protein Neighboring gene arrow Neighboring gene uncharacterized protein Neighboring gene crowded by cid

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of copper-transporting P(IB)-type ATPase function. Southon A, et al. Biometals, 2010 Aug. PMID 20372979
    2. centrosomin's beautiful sister (cbs) encodes a GRIP-domain protein that marks Golgi inheritance and functions in the centrosome cycle in Drosophila. Eisman RC, et al. J Cell Sci, 2006 Aug 15. PMID 16882688
    3. bicoid RNA localization requires the trans-Golgi network. Cai X, et al. Hereditas, 2019. PMID 31528161, Free PMC Article
    4. Age-dependent expression profiles of two adaptogenic systems and thermotolerance in Drosophila melanogaster. Shilova V, et al. Cell Stress Chaperones, 2020 Mar. PMID 32040825, Free PMC Article
    5. The Arf family G protein Arl1 is required for secretory granule biogenesis in Drosophila. Torres IL, et al. J Cell Sci, 2014 May 15. PMID 24610947, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in centrosome cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi trans cisterna IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    golgin 97
    Names
    CG4840-PA
    CG4840-PB
    CG4840-PC
    Centrosomin's beautiful sister
    Golgin97-PA
    Golgin97-PB
    Golgin97-PC
    dGolgin-97
    dementin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13450586..13453393
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137031.3 → NP_610875.1  golgin 97, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4K7
      Related
      FBpp0086786
      Conserved Domains (2) summary
      smart00755
      Location:553 → 598
      Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
      cl07893
      Location:276 → 372
      AmyAc_family; Alpha amylase catalytic domain family

    2. NM_001259368.2 → NP_001246297.1  golgin 97, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K775
      Conserved Domains (2) summary
      pfam01465
      Location:554 → 587
      GRIP; GRIP domain
      cl07893
      Location:276 → 372
      AmyAc_family; Alpha amylase catalytic domain family

    3. NM_001259369.2 → NP_001246298.1  golgin 97, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K864
      Conserved Domains (2) summary
      pfam01465
      Location:554 → 585
      GRIP; GRIP domain
      cl07893
      Location:276 → 372
      AmyAc_family; Alpha amylase catalytic domain family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K775 A0A0B4K775
    A0A0B4K864 A0A0B4K864
    Q7K4K7 Q7K4K7

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