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    Elba3 Early boundary activity 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33670, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Elba3provided by FlyBase
    Official Full Name
    Early boundary activity 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0031621
    Locus tag
    Dmel_CG15634
    See related
    AllianceGenome:FB:FBgn0031621
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15634; Dmel\CG15634; Elba
    Summary
    Enables protein-macromolecule adaptor activity. Involved in heterochromatin boundary formation. Located in nucleus. Part of chromatin silencing complex. Is expressed in neuroblasts and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Elba3 in Genome Data Viewer
    Location:
    25A3-25A3; 2-13 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4687511..4688956)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4687511..4688956)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long noncoding RNA: testis-specific 6 Neighboring gene uncharacterized protein Neighboring gene Early boundary activity 1 Neighboring gene uncharacterized protein Neighboring gene decima Neighboring gene TBP-associated factor 30kD subunit alpha-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A stage-specific factor confers Fab-7 boundary activity during early embryogenesis in Drosophila. Aoki T, et al. Mol Cell Biol, 2008 Feb. PMID 18039839, Free PMC Article
    2. The BEN Domain Protein Insensitive Binds to the Fab-7 Chromatin Boundary To Establish Proper Segmental Identity in Drosophila. Fedotova A, et al. Genetics, 2018 Oct. PMID 30082280, Free PMC Article
    3. BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila. Ueberschär M, et al. Nat Commun, 2019 Dec 13. PMID 31836703, Free PMC Article
    4. Bi-functional cross-linking reagents efficiently capture protein-DNA complexes in Drosophila embryos. Aoki T, et al. Fly (Austin), 2014. PMID 24135698, Free PMC Article
    5. Different Evolutionary Strategies To Conserve Chromatin Boundary Function in the Bithorax Complex. Cleard F, et al. Genetics, 2017 Feb. PMID 28007886, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex.
      Title: Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heterochromatin boundary formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin silencing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    early boundary activity 3
    Names
    CG15634-PA
    Elba3-PA
    early boundary factor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4687511..4688956
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135006.3 → NP_608850.1  early boundary activity 3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608850.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VR19
      Related
      FBpp0077070
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VR19.1 Q9VR19

    Gene LinkOut

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