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    sut1 sugar transporter 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35774, updated on 9-Dec-2024

    Summary

    Official Symbol
    sut1provided by FlyBase
    Official Full Name
    sugar transporter 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0028563
    Locus tag
    Dmel_CG8714
    See related
    AllianceGenome:FB:FBgn0028563
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8714; Dmel\CG8714; Sut-1; Sut1
    Summary
    Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be active in membrane. Is expressed in adult head; amnioserosa; organism; and yolk nucleus. Human ortholog(s) of this gene implicated in Fanconi-Bickel syndrome; glycogen storage disease; and type 2 diabetes mellitus. Orthologous to several human genes including SLC2A2 (solute carrier family 2 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See sut1 in Genome Data Viewer
    Location:
    44A4-44A4; 2-58 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8082976..8087151)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3970481..3974656)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene lingerer Neighboring gene Vacuolar protein sorting 28 Neighboring gene saliva Neighboring gene sugar transporter 2 Neighboring gene sugar transporter 3

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in monosaccharide transmembrane transport  
    involved_in transmembrane transport  
    Component Evidence Code Pubs
    is_active_in membrane  
    located_in membrane  

    General protein information

    Preferred Names
    sugar transporter 1
    Names
    CG8714-PA
    sut1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8082976..8087151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078934.3 → NP_523658.1  sugar transporter 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523658.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KK97
      Related
      FBpp0087855
      Conserved Domains (2) summary
      cd06174
      Location:96 → 482
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam00083
      Location:55 → 497
      Sugar_tr; Sugar (and other) transporter
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