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    mi minus [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37723, updated on 9-Dec-2024

    Summary

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    Official Symbol
    miprovided by FlyBase
    Official Full Name
    minusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261786
    Locus tag
    Dmel_CG5360
    See related
    AllianceGenome:FB:FBgn0261786
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5360; Dmel\CG5360; l(2)SH0818; l(2)SH2 0818
    Summary
    Enables SCF ubiquitin ligase complex binding activity and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; chaeta morphogenesis; and endomitotic cell cycle. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    Location:
    59E2-59E2; 2-103 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23523856..23528260)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19411379..19415783)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RabX1 Neighboring gene brown Neighboring gene pickpocket 3 Neighboring gene Gustatory receptor 59e

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of chromatin structure of genes silenced by heterochromatin in trans. Nisha P, et al. Genetics, 2008 May. PMID 18493059, Free PMC Article
    2. Drosophila Minus is required for cell proliferation and influences Cyclin E turnover. Szuplewski S, et al. Genes Dev, 2009 Sep 1. PMID 19723762, Free PMC Article
    3. Mutants affecting position-effect heterochromatinization in Drosophila melanogaster. Reuter G, et al. Chromosoma, 1982. PMID 6813058
    4. Morphogenesis of denticles and hairs in Drosophila embryos: involvement of actin-associated proteins that also affect adult structures. Dickinson WJ, et al. Cell Motil Cytoskeleton, 1997. PMID 9295137
    5. A misexpression screen to identify regulators of Drosophila larval hemocyte development. Stofanko M, et al. Genetics, 2008 Sep. PMID 18757933, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables SCF ubiquitin ligase complex binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin-like ligase-substrate adaptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in chaeta morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endomitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ovarian nurse cell to oocyte transport HMP PubMed 
    involved_in positive regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    minus
    Names
    CG5360-PA
    lethal (2) SH0818
    mi-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23523856..23528260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137959.2 → NP_611803.1  minus [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611803.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1N8
      Related
      FBpp0071967
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1N8 Q9W1N8

    Gene LinkOut

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