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    PSD pleckstrin and Sec7 domain containing [ Bos taurus (domestic cattle) ]

    Gene ID: 523124, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PSDprovided by VGNC
    Official Full Name
    pleckstrin and Sec7 domain containingprovided by VGNC
    Primary source
    VGNC:VGNC:107303
    See related
    Ensembl:ENSBTAG00000003580
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PSD in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (23026186..23042739, complement)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene golgi brefeldin A resistant guanine nucleotide exchange factor 1 Neighboring gene uncharacterized LOC132343951 Neighboring gene nuclear factor kappa B subunit 2 Neighboring gene F-box and leucine rich repeat protein 15 Neighboring gene CUE domain containing 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PH and SEC7 domain-containing protein 1
    Names
    exchange factor for ADP-ribosylation factor guanine nucleotide factor 6
    exchange factor for ARF6 A
    pleckstrin homology and SEC7 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191475.1 → NP_001178404.1  PH and SEC7 domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      BC148972, EE908163
      UniProtKB/Swiss-Prot
      A6QNS4, F1MUS9
      Related
      ENSBTAP00000004659.6, ENSBTAT00000004659.6
      Conserved Domains (3) summary
      cd00171
      Location:544 → 710
      Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
      cd13295
      Location:755 → 879
      PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
      pfam00169
      Location:759 → 867
      PH; PH domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      23026186..23042739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024985634.2 → XP_024841402.1  PH and SEC7 domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      A6QNS4, F1MUS9
      Conserved Domains (3) summary
      cd00171
      Location:544 → 710
      Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
      cd13295
      Location:755 → 883
      PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
      cl28033
      Location:27 → 183
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    2. XM_024985633.2 → XP_024841401.1  PH and SEC7 domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      A6QNS4, F1MUS9
      Conserved Domains (3) summary
      cd00171
      Location:544 → 710
      Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
      cd13295
      Location:755 → 883
      PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
      cl28033
      Location:27 → 183
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F1MUS9.1 GenPept UniProtKB/Swiss-Prot:F1MUS9

    Gene LinkOut

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    Research Materials