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    BSPRY B-box and SPRY domain containing [ Bos taurus (domestic cattle) ]

    Gene ID: 510681, updated on 1-Jan-2025

    Summary

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    Official Symbol
    BSPRYprovided by VGNC
    Official Full Name
    B-box and SPRY domain containingprovided by VGNC
    Primary source
    VGNC:VGNC:26580
    See related
    BGD:BT26930; Ensembl:ENSBTAG00000044155
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See BSPRY in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (102605178..102629728)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104969449 Neighboring gene ring finger protein 183 Neighboring gene cyclin-dependent kinase 4-like Neighboring gene WD repeat domain 31 Neighboring gene uncharacterized LOC112447844 Neighboring gene haloacid dehalogenase like hydrolase domain containing 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    B box and SPRY domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206723.1 → NP_001193652.1  B box and SPRY domain-containing protein

      See identical proteins and their annotated locations for NP_001193652.1

      Status: VALIDATED

      Source sequence(s)
      DAAA02024568, DAAA02024569
      UniProtKB/TrEMBL
      F1MKU3
      Related
      ENSBTAP00000053511.3, ENSBTAT00000061293.4
      Conserved Domains (2) summary
      cd00021
      Location:20 → 45
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd12904
      Location:232 → 401
      SPRY_BSPRY; SPRY domain in Ro-Ret family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      102605178..102629728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024995593.2 → XP_024851361.1  B box and SPRY domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F1MKU3
      Conserved Domains (2) summary
      cd00021
      Location:20 → 45
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd12904
      Location:242 → 411
      SPRY_BSPRY; SPRY domain in Ro-Ret family

    2. XM_024995594.2 → XP_024851362.1  B box and SPRY domain-containing protein isoform X2

      UniProtKB/TrEMBL
      F1MKU3
      Conserved Domains (2) summary
      cd00021
      Location:20 → 45
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd12904
      Location:241 → 410
      SPRY_BSPRY; SPRY domain in Ro-Ret family

    3. XM_010808252.3 → XP_010806554.1  B box and SPRY domain-containing protein isoform X3

      UniProtKB/TrEMBL
      F1MKU3
      Conserved Domains (2) summary
      cd00021
      Location:20 → 45
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd12904
      Location:155 → 324
      SPRY_BSPRY; SPRY domain in Ro-Ret family
    Nucleotide Protein Strain
    Heading Accession and Version

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