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    SCG5 secretogranin V [ Bos taurus (domestic cattle) ]

    Gene ID: 508224, updated on 29-Jan-2025

    Summary

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    Official Symbol
    SCG5provided by VGNC
    Official Full Name
    secretogranin Vprovided by VGNC
    Primary source
    VGNC:VGNC:34334
    See related
    BGD:BT12509; Ensembl:ENSBTAG00000032613
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    7B2; Sgne1
    Orthologs
    human mouse all
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    Genomic context

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    See SCG5 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (30003362..30062439, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene formin 1 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene gremlin 1, DAN family BMP antagonist Neighboring gene uncharacterized LOC112448433 Neighboring gene uncharacterized LOC132346357 Neighboring gene Rho GTPase activating protein 11A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Neuroendocrine protein 7B2 can be inactivated by phosphorylation within the secretory pathway. Lee SN, et al. J Biol Chem, 2006 Feb 10. PMID 16286464
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC128496

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables enzyme regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of hormone secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in secretory granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuroendocrine protein 7B2
    Names
    secretogranin V (7B2 protein)
    secretory granule, neuroendocrine protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045998.2 → NP_001039463.1  neuroendocrine protein 7B2 precursor

      See identical proteins and their annotated locations for NP_001039463.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105453
      UniProtKB/TrEMBL
      A0A3S5ZPW1, F1MC66, Q2HJG0
      Conserved Domains (1) summary
      pfam05281
      Location:25 → 198
      Secretogranin_V; Neuroendocrine protein 7B2 precursor (Secretogranin V)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      30003362..30062439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059890291.1 → XP_059746274.1  neuroendocrine protein 7B2 isoform X4

      UniProtKB/TrEMBL
      A0A3S5ZPW1

    2. XM_005211477.4 → XP_005211534.1  neuroendocrine protein 7B2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1ME41, A0A3S5ZPW1
      Related
      ENSBTAP00070048765.1, ENSBTAT00070080520.1
      Conserved Domains (1) summary
      pfam05281
      Location:25 → 181
      Secretogranin_V; Neuroendocrine protein 7B2 precursor (Secretogranin V)

    3. XM_005211476.5 → XP_005211533.1  neuroendocrine protein 7B2 isoform X1

      See identical proteins and their annotated locations for XP_005211533.1

      UniProtKB/TrEMBL
      A0A3S5ZPW1
      Related
      ENSBTAP00070048759.1, ENSBTAT00070080508.1
      Conserved Domains (1) summary
      pfam05281
      Location:25 → 199
      Secretogranin_V; Neuroendocrine protein 7B2 precursor (Secretogranin V)

    4. XM_059890290.1 → XP_059746273.1  neuroendocrine protein 7B2 isoform X2

      UniProtKB/TrEMBL
      A0A3S5ZPW1, F1MC66, Q2HJG0

    5. XM_059890289.1 → XP_059746272.1  neuroendocrine protein 7B2 isoform X1

      UniProtKB/TrEMBL
      A0A3S5ZPW1
    Nucleotide Protein Strain
    Heading Accession and Version

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