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    JUND JunD proto-oncogene, AP-1 transcription factor subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 517192, updated on 27-Dec-2024

    Summary

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    Gene symbol
    JUND
    Gene description
    JunD proto-oncogene, AP-1 transcription factor subunit
    See related
    BGD:BT17686; Ensembl:ENSBTAG00000052791
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See JUND in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (4912209..4913961)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene histone H3.3A-like Neighboring gene uncharacterized LOC101902444 Neighboring gene LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene IQ motif containing N Neighboring gene colon, intestine and stomach enriched 1 Neighboring gene uncharacterized LOC618787 Neighboring gene phosphodiesterase 4C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Bovine dialyzable leukocyte extract modulates AP-1 DNA-binding activity and nuclear transcription factor expression in MCF-7 breast cancer cells. Mendoza-Gamboa E, et al. Cytotherapy, 2008. PMID 18368600
    2. Comparative mapping of anchor loci from HSA19 to cattle chromosomes 7 and 18. Gao Q, et al. J Hered, 1997 Nov-Dec. PMID 9419894
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 DNA-binding activity and expression of several transcriptions factors in breast cancer cells.
      Title: Bovine dialyzable leukocyte extract modulates AP-1 DNA-binding activity and nuclear transcription factor expression in MCF-7 breast cancer cells.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC165728

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor JunD
    Names
    jun D proto-oncogene
    transcription factor AP-1 subunit JunD
    transcription factor jun-D

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103253.1 → NP_001096723.1  transcription factor JunD

      See identical proteins and their annotated locations for NP_001096723.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151336
      UniProtKB/Swiss-Prot
      A7YY54
      UniProtKB/TrEMBL
      A0AAA9ST87
      Related
      ENSBTAP00000082876.1, ENSBTAT00000120554.1
      Conserved Domains (2) summary
      cd14696
      Location:270 → 329
      bZIP_Jun; Basic leucine zipper (bZIP) domain of Jun proteins and similar proteins: a DNA-binding and dimerization domain
      pfam03957
      Location:1 → 257
      Jun; Jun-like transcription factor

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      4912209..4913961
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A7YY54.1 GenPept UniProtKB/Swiss-Prot:A7YY54

    Gene LinkOut

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